8. Ke T, Tsatsakis A, Santamaría A, Antunes Soare FA, Tinkov AA, Docea AO, Skalny A, Bowman AB, Aschner M. Chronic exposure to methylmercury induces puncta formation in cephalic dopaminergic neurons in Caenorhabditis elegans. Neurotoxicology. 2020; 77: 105–13.

7. Kalemaki M, Karantanas A, Exarchos D, Detorakis E, Zoras O, Marias K, Millo C, Baggi U, Pallikaris I, Stratis A, Karatzanis I, Perisinakis K, Koutentakis P, Kostadakis GA, Spandidos DA, Tsatsakis A, Papadakis GZ. PET/CT and PET/MRI in ophthalmic oncology (Review). International Journal of Oncology. 2020; 56: 417-420.

6. Hudita A, Galateanu B, Dinescu S, Costache M, Dinischiotu A, Negrei C, Stan M, Tsatsakis A, Nikitovic D, Lupuliasa D, Balanescu A. In Vitro Effects of Cetylated Fatty Acids Mixture from Celadrin on Chondrogenesis and Inflammation with Impact on Osteoarthritis. Cartilage. 2020; 11(1):88–97.

5. Iordache AM, Docea AO, Buga AM, Zlatian O, Ciurea ME, Rogoveanu OC, Burada F, Sosoi S, Mitrut R, Mamoulakis C, Albulescu D, Vasile RC, Tsatsakis A, Calina D. Sildenafil and tadalafil reduce the risk of contrast-induced nephropathy by modulating the oxidant/antioxidant balance in a murine model. Food and Chemical Toxicology. 2020; 135.

4. Hernández AF, Docea AO, Goumenou M, Sarigiannis D, Aschner M, Tsatsakis A. Application of novel technologies and mechanistic data for risk assessment under the real-life risk simulation (RLRS) approach. Food and Chemical Toxicology. 2020; 137.

3. Calabrese EJ, Calabrese V, Tsatsakis A, Giordano JJ. HORMESIS AND GINKGO BILOBA (GB): Numerous Biological Effects of GB are Mediated via Hormesis. Ageing Research Reviews. 2020; 101019.

2. Basyreva LY, Voinova EV., Gusev AA, Mikhalchik EV., Kuskov AN, Goryachaya AV., Gusev AV, Shtilman MI, Velonia K, Tsatsakis AM. Fluorouracil neutrophil extracellular traps formation inhibited by polymer nanoparticle shielding. Materials Science and Engineering C. 2020; 108.

1. Barmpas M, Vakonaki E, Tzatzarakis M, Sifakis S, Alegakis A, Grigoriadis T, Sodré DB, Daskalakis G, Antsaklis A, Tsatsakis A. Organochlorine pollutants’ levels in hair, amniotic fluid and serum samples of pregnant women in Greece. A cohort study. Environmental Toxicology and Pharmacology. 2020;73: 103279.



79. Ke T, Gonçalves FM, Gonçalves CL, dos Santos AA, Rocha JBT, Farina M, Skalny A, Tsatsakis A, Bowman AB, Aschner M. Post-translational modifications in MeHg-induced neurotoxicity. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2019; pp. 2068–2081.

78. Tsoukalas D, Sarandi E, Thanasoula M, Docea AO, Tsilimidos G, Calina D, Tsatsakis A. Metabolic Fingerprint of Chronic Obstructive Lung Diseases: A New Diagnostic Perspective. Metabolites. 2019; 9(12):290. Available from: https://www.mdpi.com/2218-1989/9/12/290

77. Tsoukalas D, Fragoulakis V, Sarandi E, Docea AO, Papakonstantinou E, Tsilimidos G, Anamaterou C, Fragkiadaki P, Aschner M, Tsatsakis A, Drakoulis N, Calina D. Targeted Metabolomic Analysis of Serum Fatty Acids for the Prediction of Autoimmune Diseases. Frontiers of Molecular Biosciences. 2019; 6:1–14.

76. Papasavva M, Katsarou M-S, Vikelis M, Mitropoulou E, Dermitzakis E V, Papakonstantinou S, Arvaniti C, Mitsikostas D-D, Gozes I, Tsatsakis AM, Drakoulis N. Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population. Journal of Molecular Neuroscience. 2019; Available from: http://link.springer.com/10.1007/s12031-019-01439-0

75. Mușat MG, Nițulescu GM, Surleac M, Tsatsakis A, Spandidos DA, Margină D. HIV 1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG mediated recombination (Review). Molecular Medicine Reports. 2019; 20(6):4749–62.

74. Kirichenko K, Zakharenko A, Pikula K, Chaika V, Markina Z, Orlova T, Medvedev SA, Waissi G, Kholodov AS, Tsatsakis AM, Golokhvast KS. Dependence of welding fume particle toxicity on electrode type and current intensity assessed by microalgae growth inhibition test. Environmental Research. 2019; 179.

73. Girvalaki C, Tzatzarakis M, Vardavas A, Kyriakos C, Nikitara K, Stivaktakis P, Tsatsakis A, Vardavas C. Discrepancies in reported versus measured nicotine content of e-cigarette refill liquids across 9 European Countries before and after the implementation of the EU Tobacco Products Directive. European Respiratory Journal. 2019; 1900941. Available from: https://browzine.com/articles/356627778

72. Babar U, Nawaz MA, Arshad U, Azhar MT, Atif RM, Golokhvast KS, Tsatsakis AM, Scherbakova K, Chung G, Rana IA. Transgenic crops for the agricultural improvement in Pakistan: a perspective of environmental stresses and the current status of genetically modified crops. GM Crops Food. 2019; 1–29. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31679447

71. Fountoucidou P, Veskoukis AS, Kerasioti E, Docea AO, Taitzoglou IA, Liesivuori J, Tsatsakis A, Kouretas D. A mixture of routinely encountered xenobiotics induces both redox adaptations and perturbations in blood and tissues of rats after a long-term low-dose exposure regimen: The time and dose issue. Toxicology Letters. 2019; 317:24–44.

70. Girvalaki C, Vardavas A, Tzatzarakis M, Kyriakos CN, Nikitara K, Tsatsakis AM, Vardavas CI. Compliance of e-cigarette refill liquids with regulations on labelling, packaging and technical design characteristics in nine European member states. Tobacco Control. 2019.

69. Krasanakis T, Nikolouzakis TK, Sgantzos M, Mariolis Sapsakos T, Souglakos J, Spandidos DA, Tsitsimpikou C, Tsatsakis A, Tsiaoussis J. Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review). Oncology Reports. 2019.

68. Pikula KS, Chernyshev V, Zakharenko AM, Chaika VV, Waissi G, Hai LH, Hien TT, Tsatsakis AM, Golokhvast KS. Toxicity assessment of particulate matter emitted from different types of vehicles on marine microalgae. Environmental Research. 2019.

67. Tuaeva NO, Falzone L, Porozov YB, Nosyrev AE, Trukhan VM, Kovatsi L, Spandidos DA, Drakoulis N, Kalogeraki A, Mamoulakis C, Tzanakakis G, Libra M, Tsatsakis A. Translational Application of Circulating DNA in Oncology: Review of the Last Decades Achievements. Cells. 2019; 8(10):E1251.

66. Akinyemi AJ, Miah MR, Ijomone OM, Tsatsakis A, Soares FAA, Tinkov AA, Skalny AV, Venkataramani V, Aschner M. Lead (Pb) exposure induces dopaminergic neurotoxicity in Caenorhabditis elegans: Involvement of the dopamine transporter. Toxicology Reports. 2019; 6:833–40. doi: 10.1016/j.toxrep.2019.08.001.

65. Gaforio JJ, Visioli F, Alarcón-de-la-Lastra C, Castañer O, Delgado-Rodríguez M, Fitó M, Hernández AF, Huertas JR, Martinez-González MA, Menendez JA, De la Osada J, Papadaki A, Parron T, Pereira JE, Rosillo MA, Sanchez-Quesada C, Schwingshackl L, Toledo E, Tsatsakis AM. Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018. Nutrients. 2019; 11(9):2039. doi:10.3390/nu11092039.

64. Karzi V, Tzatzarakis M, Katsikantami I, Stavroulaki A, Alegakis A, Vakonaki E, Xezonaki P, Sifakis S, Rizos A, Tsatsakis A. Investigating exposure to endocrine disruptors via hair analysis of pregnant women. Environmental Research. 2019; 178:108692. doi: 10.1016/j.envres.2019.108692.

63. Trivizakis E, Ioannidis G, Melissianos V, Papadakis G, Tsatsakis A, Spandidos D, Marias K. A novel deep learning architecture outperforming ‘off the shelf’ transfer learning and feature based methods in the automated assessment of mammographic breast density. Oncology Reports. 2019; 2009–2015. doi: 10.3892/or.2019.7312.

62. Tsatsakis A, Docea AO, Constantin C, Calina D, Zlatian O, Nikolouzakis TK, Stivaktakis PD, Kalogeraki A, Liesivuori J, Tzanakakis G, Neagu M. Genotoxic, cytotoxic, and cytopathological effects in rats exposed for 18 months to a mixture of 13 chemicals in doses below NOAEL levels. Toxicology Letters. 2019. doi: 10.1016/j.toxlet.2019.09.004.

61. Tsoukalas D, Fragkiadaki P, Docea A, Alegakis A, Sarandi E, Thanasoula M, Spandidos DA, Tsatsakis A, Petrovna Razgonova M, Calina D. Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives. Molecular Medicine Reports. 2019; 3701–3708. doi: 10.3892/mmr.2019.10614.

60. Hernández AF, Buha A, Constantin C, Wallace DR, Sarigiannis D, Neagu M, Antonijevic B, Wallace Hayes A, Wilks MF, Tsatsakis A. Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures. Archives of Toxicology. 2019. doi: 10.1007/s00204-019-02547-x.

59. Zanfirescu A, Ungurianu A, Tsatsakis AM, Nițulescu GM, Kouretas D, Veskoukis A, Tsoukalas D, Engin AB, Aschner M, Margina D. A Review of the Alleged Health Hazards of Monosodium Glutamate. Comprehensive Reviews in Food Science and Food Safety. Comprehensive Reviews in Food Science and Food Safety. 2019; 18(4): 1111-1134. doi: 10.1111/1541-4337.12448.

58. Tsatsakis A, Docea AO, Calina D, Tsarouhas K, Zamfira L-M, Mitrut R, Sharifi-Rad J, Kovatsi L, Siokas V, Dardiotis E, Drakoulis N, Lazopoulos G, Tsitsimpikou C, Mitsias P, Neagu M. A Mechanistic and Pathophysiological Approach for Stroke Associated with Drugs of Abuse. Journal of Clinical Medicine. 2019; 8(9). doi: 10.3390/jcm8091295.

57. Drăghici GA, Dehelean C, Pinzaru I, Bordean DM, Borozan A, Tsatsakis AM, Kovatsi L, Nica D. Soil copper uptake by land snails: A semi-field experiment with juvenile Cantareus aspersus snails. Environmental Toxicology and Pharmacology. 2019; 72: 103243.  doi: 10.1016/j.etap.2019.103243.

56. Ruszkiewicz JA, Tinkov AA, Skalny A V, Siokas V, Dardiotis E, Tsatsakis A, Bowman AB, da Rocha JBT, Aschner M. Brain diseases in changing climate. Environmental Research. 2019; 177: 108637. doi: 10.1016/j.envres.2019.108637.

55. Rezaee R, Sheidary A, Jangjoo S, Ekhtiary S, Bagheri S, Kohkan Z, Dadres M, Oana Docea A, Tsarouhas K, Sarigiannis DA, Karakitsios S, Tsatsakis A, Kovatsi L, Hashemzaei M. Cardioprotective effects of hesperidin on carbon monoxide poisoned in rats. Drug and Chemical Toxicology. 2019; 1–6. doi: 10.1080/01480545.2019.1650753.

54. Silantyev AS, Falzone L, Libra M, Gurina OI, Kardashova KS, Nikolouzakis TK, Nosyrev AE, Sutton CW, Mitsias PD, Tsatsakis A. Current and Future Trends on Diagnosis and Prognosis of Glioblastoma: From Molecular Biology to Proteomics. Cells. 2019; 8(8). doi: 10.3390/cells8080863.

53. Tsatsakis A, Tyshko N V, Docea AO, Shestakova SI, Sidorova YS, Petrov NA, Zlatian O, Mach M, Hartung T, Tutelyan VA. The effect of chronic vitamin deficiency and long term very low dose exposure to 6 pesticides mixture on neurological outcomes - a Real-Life Risk Simulation approach. Toxicology Letters. 2019. doi: 10.1016/j.toxlet.2019.07.026.

52. Karaulov A V, Renieri EA, Smolyagin AI, Mikhaylova I V, Stadnikov AA, Begun DN, Tsarouhas K, Buha Djordjevic A, Hartung T, Tsatsakis A. Long-term effects of chromium on morphological and immunological parameters of Wistar rats. Food and Chemical Toxicology. 2019; 133: 110748. doi: 10.1016/j.fct.2019.110748.

51. Hernández AF, Lozano-Paniagua D, González-Alzaga B, Kavvalakis MP, Tzatzarakis MN, López-Flores I, Aguilar-Grduno C, Caparros-Gonzalez RA, Tsatsakis AM, Lacasana M. Biomonitoring of common organophosphate metabolites in hair and urine of children from an agricultural community. Environment International. 2019; 131: 104997. doi: 10.1016/j.envint.2019.104997.

50. Goumenou M, Tsatsakis A. Proposing new approaches for the risk characterisation of single chemicals and chemical mixtures: The source related Hazard Quotient (HQS) and Hazard Index (HIS) and the adversity specific Hazard Index (HIA). Toxicology reports. 2019; 6: 632–6.  doi: 10.1016/j.toxrep.2019.06.010.

49. Nawaz MA, Zakharenko AM, Zemchenko IV, Haider MS, Ali MA, Imtiaz M, Chung G, Tsatsakis A, Sun S, Golokhvast KS. Phytolith Formation in Plants: From Soil to Cell. Plants (Basel, Switzerland.) 2019; 8(8). doi: 10.3390/plants8080249.

48. Stancioiu F, Mihai D, Papadakis GZ, Tsatsakis A, Spandidos DA, Badiu C. Treatment for benign thyroid nodules with a combination of natural extracts. Molecular Medicine Reports. 2019; 20(3): 2332–8.  doi: 10.3892/mmr.2019.10453.

47. Stamati P, Siokas V, Aloizou A-M, Karampinis E, Arseniou S, Rakitskii VN, Tsatsakis A, Spandidos DA, Gozes I, Mitsias PD, Bogdanos DP, Hadjigeorgiou GM, Dardiotis E. Does SCFD1 rs10139154 Polymorphism Decrease Alzheimer’s Disease Risk? Journal of Molecular Neuroscience. 2019. doi: 10.1007/s12031-019-01363-3.

46. Kavasi R-M, Berdiaki A, Spyridaki I, Papoutsidakis A, Corsini E, Tsatsakis A, Tzanakakis GN, Nikitovic D. Contact allergen (PPD and DNCB)-induced keratinocyte sensitization is partly mediated through a low molecular weight hyaluronan (LMWHA)/TLR4/NF-κB signaling axis. Toxicology and Applied Pharmacology. 2019; 377: 114632. doi: 10.1016/j.taap.2019.114632.

45. Vasilopoulos E, Fragkiadaki P, Kalliora C, Fragou D, Docea AO, Vakonaki E, Tsoukalas D, Calina D, Buga AM, Georgiadis G, Mamoulakis C, Makrigiannakis A, Spandidos DA, Tsatsakis A. The association of female and male infertility with telomere length (Review). International Journal of Molecular Medicine. 2019; 44(2): 375–89. doi: 10.3892/ijmm.2019.4225.

44. Neagu M, Constantin C, Popescu ID, Zipeto D, Tzanakakis G, Nikitovic D, Fenga C, Stratakis CA, Spandidos DA, Tsatsakis AM. Inflammation and Metabolism in Cancer Cell-Mitochondria Key Player. Frontiers in Oncology. 2019; 9: 348. doi: 10.3389/fonc.2019.00348.

43. Taghizadeh SF, Goumenou M, Rezaee R, Alegakis T, Kokaraki V, Anesti O, Sarigiannis DA, Tsatsakis A, Karimi G. Cumulative risk assessment of pesticide residues in different Iranian pistachio cultivars: Applying the source specific HQS and adversity specific HIA approaches in Real Life Risk Simulations (RLRS). Toxicology Letters. 2019; 313: 91–100. doi: 10.1016/j.toxlet.2019.05.019.

42. Tsoukalas D, Fragkiadaki P, Docea AO, Alegakis AK, Sarandi E, Vakonaki E, Salataj E, Kouvidi E, Nikitovic D, Kovatsi L, Spandidos DA, Tsatsakis A, Calina D. Association of nutraceutical supplements with longer telomere length. International Journal of Molecular Medicine. 2019; 44(1): 218–26. doi: 10.3892/ijmm.2019.4191.

41. Wallace DR, Spandidos DA, Tsatsakis A, Schweitzer A, Djordjevic V, Djordjevic AB. Potential interaction of cadmium chloride with pancreatic mitochondria: Implications for pancreatic cancer. International Journal of Molecular Medicine. 2019; 44(1): 145–56. doi: 10.3892/ijmm.2019.4204.

40. Olaru OT, Zanfirescu A, Nitulescu GM, Nitulescu G, Dinu-Pirvu CE, Anuta V, Tsatsakis A, Spandidos DA, Margina D, Seremet OC. Predictive power of the Triticum root elongation test for the assessment of novel anti proliferative therapies. International Journal of Molecular Medicine. 2019; 44(1): 16–24. doi: 10.3892/ijmm.2019.4192.

39. Ghazanfarpour M, Najafi MN, Roozbeh N, Mashhadi ME, Keramat-Roudi A, Mégarbane B, Tsatsakis A, Moghaddam MMM, Rezaee R. Therapeutic approaches for neonatal abstinence syndrome: a systematic review of randomized clinical trials. Daru. 2019; 27(1): 423–31. doi: 10.1007/s40199-019-00266-3.

38. Mamoulakis C, Fragkiadoulaki I, Karkala P, Georgiadis G, Zisis I-E, Stivaktakis P, Kalogeraki A, Tsiaoussis I, Burykina T, Lazopoulos G, Tsarouhas K, Kouretas D, Tsatsakis A. Contrast-induced nephropathy in an animal model: Evaluation of novel biomarkers in blood and tissue samples. Toxicology reports. 2019; 6: 395–400. doi: 10.1016/j.toxrep.2019.04.007.

37. Dardiotis E., Aloizou A. M., Siokas V., Tsouris Z., Rikos D., Marogianni C., … Tsatsakis A. (2019). Paraoxonase-1 genetic polymorphisms in organophosphate metabolism. Toxicology, 411, 24–31. doi: 10.1016/j.tox.2018.10.012.

36. Docea A. O., Goumenou M., Calina D., Arsene A. L., Dragoi C. M., Gofita E., … Tsatsakis A. (2019). Adverse and hormetic effects in rats exposed for 12 months to low dose mixture of 13 chemicals: RLRS part III. Toxicology Letters, 310, 70–91. doi: 10.1016/j.toxlet.2019.04.005.

35. Govorushko S., Rezaee R., Dumanov J., & Tsatsakis A. (2019). Poisoning associated with the use of mushrooms: A review of the global pattern and main characteristics. Food and Chemical Toxicology, 128, 267–279. doi: 10.1016/j.fct.2019.04.016.

34. Lee H. J., Spandidos D. A., Tsatsakis A., Margina D., Izotov B. N., & Yang S. H. (2019). Neuroprotective effects of Scrophularia buergeriana extract against glutamate-induced toxicity in SH-SY5Y cells. International Journal of Molecular Medicine, 43(5), 2144–2152. doi: 10.3892/ijmm.2019.4139.

33. Papadakis G., Karantanas A., Tsikankis M., Tsatsakis A., Spandidos D., & Marias K. (2019). Deep learning opens new horizons in personalized medicine (Review). Biomedical Reports, 215–217. doi: 10.3892/br.2019.1199.

32. Radu I. C., Hudita A., Zaharia C., Galateanu B., Iovu H., Tanasa E. V., … Tsatsakis A., … Costache, M. (2019). Poly (3-hydroxybutyrate-CO-3-hydroxyvalerate) PHBHV biocompatible nanocarriers for 5-FU delivery targeting colorectal cancer. Drug Delivery, 26(1), 318–327. doi: 10.1080/10717544.2019.1582729.

31. Renieri E. A., Goumenou M., Kardonsky D. A., Veselov V. V., Alegakis A., Buha A., … Tsatsakis A. (2019). Indicator PCBs in farmed and wild fish in Greece - Risk assessment for the Greek population. Food and Chemical Toxicology, 127, 260–269. doi: 10.1016/j.fct.2019.03.027.

30. Taghizadeh S. F., Rezaee R., Mehmandoust M., Madarshahi F. S., Tsatsakis A., & Karimi G. (2019). Coronatine elicitation alters chemical composition and biological properties of cumin seed essential oil. Microbial Pathogenesis, 130, 253–258. doi: 10.1016/j.micpath.2019.03.023.

29. Tsatsakis A., Goumenou M., Liesivuori J., Dekant W., & Hernández A. F. (2019). Toxicology for real-life risk simulation – Editorial preface to this special issue. Toxicology Letters, 309, 33–34. doi: 10.1016/j.toxlet.2018.12.003.

28. Tsiaoussis J., Antoniou M. N., Koliarakis I., Mesnage R., Vardavas C. I., Izotov B. N., … Tsatsakis A. (2019). Effects of single and combined toxic exposures on the gut microbiome: current knowledge and future directions. Toxicology Letters, 312, 72–97. doi: 10.1016/j.toxlet.2019.04.014.

27. Tzanakakis G., Neagu M., Tsatsakis A., & Nikitovic D. (2019). Proteoglycans and Immunobiology of Cancer—Therapeutic Implications. Frontiers in Immunology, 10, 1–8. doi: 10.3389/fimmu.2019.00875.

26. Sevim Ç., Çomaklı S., Taghizadehghalehjoughi A., Özkaraca M., Mesnage R., Kovatsi L., Burykina T. I., Kalogeraki A., Antoniou M. N., Tsatsakis A. (2019). An imazamox-based herbicide causes apoptotic changes in rat liver and pancreas. Toxicology Reports, 6, 42–50. doi: 10.1016/j.toxrep.2018.11.008.

25. Nica D.V., Draghici G.A., Andrica F.M., Popescu S., Coricovac D.E., Dehelean C.A., Gergen I.I., Kovatsi L., Coleman M.D., Tsatsakis A. (2019). Short-term effects of very low dose cadmium feeding on copper, manganese and iron homeostasis: A gastropod perspective. Environmental Toxicology and Pharmacology, 65, 9–13. doi: 10.1016/j.etap.2018.10.005.

24. Tsoukalas D., Alegakis A.K., Fragkiadaki P., Papakonstantinou E., Tsilimidos G., Geraci F., Sarandi E., Nikitovic D., Spandidos D.A., Tsatsakis A. (2019). Application of metabolomics part II: Focus on fatty acids and their metabolites in healthy adults. International Journal of Molecular Medicine, 43(1), 233–242. doi: 10.3892/ijmm.2018.3989.

23. Dardiotis E., Aloizou A.M., Siokas V., Patrinos G.P., Deretzi G., Mitsias P., Aschner M., Tsatsakis A. (2018). The Role of MicroRNAs in Patients with Amyotrophic Lateral Sclerosis. Journal of Molecular Neuroscience. doi: 10.1007/s12031-018-1204-1.

22. Katsikantami I., Colosio C., Alegakis A., Tzatzarakis M.N., Vakonaki E., Rizos A.K., Sarigiannis D.A., Tsatsakis, A.M. (2019). Estimation of daily intake and risk assessment of organophosphorus pesticides based on biomonitoring data – The internal exposure approach. Food and Chemical Toxicology, 123(October 2018), 57–71. doi: 10.1016/j.fct.2018.10.047.

21. Bagheri G., Rezaee R., Tsarouhas K., Docea A., Shahraki J., Shahriari M., Wilks M. F., Jahantigh H., Tabrizian K., Moghadam A., Bagheri S., Spandidos D. A., Tsatsakis A., Hashemzaei M. (2019). Magnesium sulfate ameliorates carbon monoxide induced cerebral injury in male rats. Molecular Medicine Reports, 19(2), 1032–1039. doi: 10.3892/mmr.2018.9771.

20. Boda D., Tsatsakis A. (2019). [Editorial] The Second Conference of the Romanian Society of Immuno Dermatology, Bucharest, September 27-29, 2018. Experimental and Therapeutic Medicine, 17(2), 979–981. doi: 10.3892/etm.2018.7067.

19. Calina D., Docea A., Golokhvast K., Sifakis S., Tsatsakis A., Makrigiannakis A. (2019). Management of Endocrinopathies in Pregnancy: A Review of Current Evidence. International Journal of Environmental Research and Public Health, 16(5), 781. doi: 10.3390/ijerph16050781.

18. Chernyshev V. V., Zakharenko A. M., Ugay S. M., Hien T. T., Hai L. H., Olesik S. M., Kholodov A. S., Zubko E., Kokkinakis M., Burykina T. I., Stratidakis A. K., Mezhuev Ya. O., Sarigiannis D. A., Tsatsakis A., Golokhvast K. S. (2019). Morphological and chemical composition of particulate matter in buses exhaust. Toxicology Reports, 6, 120–125. doi: 10.1016/j.toxrep.2018.12.002.

17. Çomaklı S., Sevim Ç., Kontadakis G., Doğan E., Taghizadehghalehjoughi A., Özkaraca M., Aschner M., Nikolouzakis T.-K., Tsatsakis A. (2019). Acute glufosinate-based herbicide treatment in rats leads to increased ocular interleukin-1β and c-Fos protein levels, as well as intraocular pressure. Toxicology Reports, 6, 155–160. doi: 10.1016/j.toxrep.2019.01.004.

16. Dardiotis E., Aloizou A.-M., Markoula S., Siokas V., Tsarouhas K., Tzanakakis G., Libra M., Kyritsis A. P., Brotis A. G., Aschner M., Gozes I., Bogdanos D. P., Spandidos D. A., Mitsias P. D., Tsatsakis A. (2019). Cancer-associated stroke: Pathophysiology, detection and management (Review). International Journal of Oncology, 54(3), 779–796. doi: 10.3892/ijo.2019.4669.

15. Eslamizad S., Kobarfard F., Tsitsimpikou C., Tsatsakis A. M., Tabib K., Yazdanpanah H. (2019). Health risk assessment of acrylamide in bread in Iran using LC-MS/MS. Food and Chemical Toxicology, 126, 162–168. doi: 10.1016/j.fct.2019.02.019.

14. Henrich-Noack P., Nikitovic D., Neagu M., Docea A. O., Engin A. B., Gelperina S., Shtilman M., Mitsias P., Tzanakakis G., Gozes I., Tsatsakis A. (2019). The blood–brain barrier and beyond: Nano-based neuropharmacology and the role of extracellular matrix. Nanomedicine: Nanotechnology, Biology and Medicine. doi: 10.1016/j.nano.2019.01.016.

13. Iatrou E. I., Tsygankov V., Seryodkin I., Tzatzarakis M. N., Vakonaki E., Barbounis E., Zakharenko A. M., Chaika V. V., Sergievich A. A., Tsatsakis A. M., Golokhvast K. (2019). Monitoring of environmental persistent organic pollutants in hair samples collected from wild terrestrial mammals of Primorsky Krai, Russia. Environmental Science and Pollution Research. doi: 10.1007/s11356-019-04171-9.

12. Ilyushina N., Goumenou M., Stivaktakis P. D., Vardavas A. I., Masaltsev G., Averianova N., Dmitricheva O., Revazova Y., Tsatsakis A. M., Rakitskii V. (2019). Maximum tolerated doses and erythropoiesis effects in the mouse bone marrow by 79 pesticides’ technical materials assessed with the micronucleus assay. Toxicology Reports, 6, 105–110. doi: 10.1016/j.toxrep.2018.12.006.

11. Mitroi M., Albulescu D., Capitanescu A., Docea A., Musat G., Mitroi G., Zlatian O., Tsatsakis A., Tzanakakis G., Spandidos D. A., Calina D. (2019). Differences in the distribution of CD20, CD3, CD34 and CD45RO in nasal mucosa and polyps from patients with chronic rhinosinusitis. Molecular Medicine Reports. doi:  10.3892/mmr.2019.9932.

10. Nawaz M. A., Mesnage R., Tsatsakis A. M., Golokhvast K. S., Yang S. H., Antoniou M. N., Chung G. (2019). Addressing concerns over the fate of DNA derived from genetically modified food in the human body: A review. Food and Chemical Toxicology, 124, 423–430. doi: 10.1016/j.fct.2018.12.030.

9. Nikolouzakis T., Stivaktakis P., Apalaki P., Kalliantasi K., Mariolis-Sapsakos T., Spandidos D. A., Tsatsakis A., Souglakos J., Tsiaoussis J. (2019). Effect of systemic treatment on the micronuclei frequency in the peripheral blood of patients with metastatic colorectal cancer. Oncology Letters, 17(3), 2703–2712. doi: 10.3892/ol.2019.9895.

8. Razgonova M., Veselov V., Zakharenko A., Golokhvast K., Nosyrev A., Cravotto G., Tsatsakis A., Spandidos D. (2019). Panax ginseng components and the pathogenesis of Alzheimer’s disease (Review). Molecular Medicine Reports. doi: 10.3892/mmr.2019.9972.

7. Renieri E. A., Safenkova I. V., Alegakis A. Κ., Slutskaya E. S., Kokaraki V., Kentouri M., Dzantiev B. B., Tsatsakis A. M. (2019). Cadmium, lead and mercury in muscle tissue of gilthead seabream and seabass: Risk evaluation for consumers. Food and Chemical Toxicology, 124, 439–449. doi: 10.1016/j.fct.2018.12.020.

6. Ruszkiewicz J. A., Miranda-Vizuete A., Tinkov A. A., Skalnaya M. G., Skalny A. V., Tsatsakis A., Aschner M. (2019). Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease. Journal of Molecular Neuroscience, 67(2), 312–342. doi: 10.1007/s12031-018-1241-9.

5. Siokas V., Kardaras D., Aloizou A.-M., Asproudis I., Boboridis K. G., Papageorgiou E., Spandidos D. A., Tsatsakis A., Tsironi E. E., Dardiotis E. (2019). Lack of Association of the rs11655081 ARSG Gene with Blepharospasm. Journal of Molecular Neuroscience, 67(3), 472–476. doi: 10.1007/s12031-018-1255-3.

4. Tavassoli M., Afshari A., Arsene A. L., Mégarbane B., Dumanov J., Bastos Paoliello M. M., Tsatsakis A., Carvalho F., Hashemzaei M., Karimi G., Rezaee R. (2019). Toxicological profile of Amanita virosa – A narrative review. Toxicology Reports, 6, 143–150. doi: 10.1016/j.toxrep.2019.01.002.

3. Tsatsakis A. M., Stratidakis A. K., Goryachaya A. V., Tzatzarakis M. N., Stivaktakis P. D., Docea A. O., Berdiaki Ai., Nikitovic D., Velonia K., Shtilman M. I., Rizos A. K., Kuskov A. N. (2019). In vitro blood compatibility and in vitro cytotoxicity of amphiphilic poly-N-vinylpyrrolidone nanoparticles. Food and Chemical Toxicology, 127, 42–52. doi: 10.1016/j.fct.2019.02.041.

2. Tsatsakis A. M., Docea A. O., Calina D., Buga A. M., Zlatian O., Gutnikov S., Kostoff R. N., Aschner M. (2019). Hormetic Neurobehavioral effects of low dose toxic chemical mixtures in real-life risk simulation (RLRS) in rats. Food and Chemical Toxicology, 125, 141–149. doi: 10.1016/j.fct.2018.12.043.

1. Tsatsakis A., Tsoukalas D., Fragkiadaki P., Vakonaki E., Tzatzarakis M., Sarandi E., Nikitovic D., Tsilimidos G., Alegakis, A. K. (2019). Developing BIOTEL: A Semi-Automated Spreadsheet for Estimating Telomere Length and Biological Age. Frontiers in Genetics, 10, 84. doi: 10.3389/fgene.2019.00084.





58. Pikula K. S., Zakharenko A. M., Chaika V. V., Stratidakis A. K., Kokkinakis M., Waissi G., Rakitskii V. N., Sarigiannis D. A., Hayes M. D., Coleman M. D., Tsatsakis A., Golokhvast K. S. (2019). Toxicity bioassay of waste cooking oil-based biodiesel on marine microalgae. Toxicology Reports, 6, 111–117. doi: 10.1016/j.toxrep.2018.12.007.

57. Tsatsakis A., Goumenou M., Liesivuori J., Dekant W., Hernández A. F. (2018). Toxicology for Real-Life Risk Simulation - Editorial Preface to this Special Issue. Toxicology Letters. doi: 10.1016/j.toxlet.2018.12.003.

56. Zlatian O., Balasoiu A., Balasoiu M., Cristea O., Docea A., Mitrut R., Spandidos D. A., Tsatsakis A. M., Bancescu G., Calina D. (2018). Antimicrobial resistance in bacterial pathogens among hospitalised patients with severe invasive infections. Experimental and Therapeutic Medicine, 16(6), 4499–4510. doi: 10.3892/etm.2018.6737

55. Kirichenko K.Y., Agoshkov A.I., Drozd V.A., Gridasov A.V., Kholodov A.S., Kobylyakov S.P., Kosyanov D.Yu., Zakrarenko A.M., Karabtsov A.A., Shimanskii S.R., Stratidakis A.K., Mezhuev Ya.O., Tsatsakis A.M., Golokhvast K.S. (2018). Characterization of fume particles generated during arc welding with various covered electrodes. Scientific Reports, 8(1), 17169. doi: 10.1038/s41598-018-35494-1.

54. Tsatsakis A.M., Vassilopoulou L., Kovatsi L., Tsitsimpikou C., Karamanou M., Leon G., Liesivuori J., Hayes A.W., Spandidos D.A. (2018). The dose response principle from philosophy to modern toxicology: The impact of ancient philosophy and medicine in modern toxicology science. Toxicology Reports, 5(October), 1107–1113. doi: 10.1016/j.toxrep.2018.10.001.

53. Aggelidakis J., Berdiaki A., Nikitovic D., Papoutsidakis A., Papachristou D.J., Tsatsakis A.M., Tzanakakis G.N. (2018). Biglycan Regulates MG63 Osteosarcoma Cell Growth Through a LPR6/β-Catenin/IGFR-IR Signaling Axis. Frontiers in Oncology, 8(October), 1–15. doi: 10.3389/fonc.2018.00470.

52. Karimani A., Mohammadpour A.H., Zirak M.R., Rezaee R., Megarbane B., Tsatsakis, A., Karimi G. (2018). Antidotes for aluminum phosphide poisoning – An update. Toxicology Reports, 5(October), 1053–1059. doi: 10.1016/j.toxrep.2018.10.009.

51. Ke T., Gonçalves F.M., Gonçalves C.L., Antunes dos Santos A.A., Rocha J.B.T., Farina M., Skalny A., Tsatsakis A., Bowman A.B., Aschner M. (2018). Post-translational modifications in MeHg-induced neurotoxicity. Biochimica et Biophysica Acta - Molecular Basis of Disease. doi: 10.1016/j.bbadis.2018.10.024.

50. Girvalaki C., Tzatzarakis M., Kyriakos C.N., Vardavas A.I., Stivaktakis P.D., Kavvalakis M., Tsatsakis A., Vardavas C. (2018). Composition and chemical health hazards of the most common electronic cigarette liquids in nine European countries. Inhalation Toxicology, 0(0), 1–9. doi: 10.1080/08958378.2018.1527879.

49. Dardiotis E., Aloizou A.M., Siokas V., Tsouris Z., Rikos D., Marogianni C., Aschner M., Kovatsi L., Bogdanos D.P., Tsatsakis, A. (2019). Paraoxonase-1 genetic polymorphisms in organophosphate metabolism. Toxicology, 411, 24–31. doi: 10.1016/j.tox.2018.10.012.

48. Nitulescu G.M., Van De Venter M., Nitulescu G., Ungurianu A., Juzenas P., Peng Q., Tuborel Olaru O., Gradinaru D., Tsatsakis A., Tsoukalas D., Spandidos D.A., Margina D. (2018). The Akt pathway in oncology therapy and beyond (Review). International Journal of Oncology, 53(6), 2319–2331. doi: 10.3892/ijo.2018.4597.

47. Limban C., Nuţă D.C., Chiriţă C., Negreș S., Arsene A.L., Goumenou M., Karakitsios S.P., Tsatsakis A.M., Sarigiannis D.A. (2018). The use of structural alerts to avoid the toxicity of pharmaceuticals. Tox. Rep. 5, 943–953. doi: 10.1016/j.toxrep.2018.08.017.

46. Tsitsimpikou C., Tsarouhas K., Vasilaki F., Papalexis P., Dryllis G., Choursalas A., Spandidos D.A., Tsatsakis A., Charvalos E., Bacopoulou F. (2018). Health risk behaviors among high school and university adolescent students. Exp. Ther. Med. 16, 3433-3438. doi: 10.3892/etm.2018.6612.

45. Kouka P., Chatzieffraimidi G.A., Raftis G., Stagos D., Angelis A., Stathopoulos P., Xynos N., Skaltsounis A.-L., Tsatsakis A.M., Kouretas D. (2018). Antioxidant effects of an olive oil total polyphenolic fraction from a Greek Olea europaea variety in different cell cultures. Phytomedicine, 47, 135–142. doi: 10.1016/j.phymed.2018.04.054.

44. Dardiotis E., Siokas V., Gara, A., Paraskevaidis E., Kyrgiou M., Xiromerisiou G., Deligeoroglou E., Galazios G., Kontomanolis E.N., Spandidos D.A., Tsatsakis A., Daponte A. (2018). Genetic variations in the SULF1 gene alter the risk of cervical cancer and precancerous lesions. Oncol. Lett. 3833–3841. doi:10.3892/ol.2018.9104.

43. Bostan H.B., Taghdisi S.M., Bowen J.L., Demertzis N., Rezaee R., Panahi, Y., Tsatsakis A.M., Karimi G. (2018). Determination of microcystin-LR, employing aptasensors. Biosens. Bioelectron. 119, 110–118. doi:10.1016/J.BIOS.2018.08.003.

42. Corsini E., Engin A.B., Neagu M., Galbiati V., Nikitovic D., Tzanakakis G., Tsatsakis A.M. (2018). Chemical-induced contact allergy: from mechanistic understanding to risk prevention. Arch. Toxicol. doi:10.1007/s00204-018-2283-z.

41. Antunes Dos Santos A., Ferrer B., Marques Gonçalves F., Tsatsakis A.M., Renieri E.A., Skalny A.V., Farina M., Rocha J.B.T., Aschner M. (2018). Oxidative Stress in Methylmercury - Induced Cell Toxicity. Toxics, 6, 47. doi:10.3390/toxics6030047.

40. Georgiadis G., Mavridis C., Belantis C., Zisis I.E., Skamagkas I., Fragkiadoulaki I., Heretis I., Tzortzis V., Psathakis K., Tsatsakis A.M., Mamoulakis C. (2018). Nephrotoxicity issues of organophosphates. Toxicology. pii: S0300-483X(18)30188-4. doi:10.1016/j.tox.2018.07.019.

39. Tsiaoussis J., Hatzidaki E., Docea A.O., Nikolouzakis T.K., Petrakis D., Burykina T., Mamoulakis C., Makrigiannakis A., Tsatsakis A. (2018). Molecular and clinical aspects of embryotoxicity induced by acetylcholinesterase inhibitors. Toxicology. pii: S0300-483X(18)30187-2. doi: 10.1016/j.tox.2018.07.018.

38. Taghizadehghalehjoughi A., Hacimuftuoglu A., Cetin M., Ugur A.B., Galateanu B., Mezhuev Y., Okkay U., Taspinar N., Taspinar M., Uyanik A., Gundogdu B., Mohammadzadeh M., Nalci K.A., Stivaktakis P., Tsatsakis A., Jung T.W., Jeong J.H., El-Aty, A.A. (2018). Effect of metformin/irinotecan-loaded poly-lactic-co-glycolic acid nanoparticles on glioblastoma: In vitro and in vivo studies. Nanomedicine, 13(13), 1595–1606. doi: 10.2217/nnm-2017-0386.

37. Tabrizian K., Shahriari Z., Rezaee R., Jahantigh H., Bagheri G., Tsarouhas K., Docea A.O., Tsatsakis A., Hashemzaei M. (2018). Cardioprotective effects of insulin on carbon monoxide-induced toxicity in male rats. Hum. Exp. Toxicol. doi: 10.1177/0960327118788134.

36. Katsarou M.-S., Papasavva M., Latsi R., Toliza I., Gkaros A.-P., Papakonstantinou S., Gatzonis S., Mitsikostas D.-D., Kovatsi L., Isotov B.N., Tsatsakis A.M., Drakoulis N. (2018). Population-Based Analysis of Cluster Headache-Associated Genetic Polymorphisms. J. Mol. Neurosci. 1–10. doi: 10.1007/s12031-018-1103-5.

35.Pikula K.S., Zakharenko A.M., Chaika V.V., Vedyagin A.A., Orlova T.Y., Mishakov I.V., Kuznetsov V.L., Park S., Renieri E.A., Kahru A., Tsatsakis A.M., Golokhvast K.S. (2018). Effects of carbon and silicon nanotubes and carbon nanofibers on marine microalgae Heterosigma akashiwo. Environ. Res. 166(June), 473–480. doi: 10.1016/j.envres.2018.06.005.

34. Buha A., Matovic V., Antonijevic B., Bulat Z., Curcic M., Renieri E. A., Tsatsakis A.M., Schweitzer A., Wallace D. (2018). Overview of cadmium thyroid disrupting effects and mechanisms. Int. J. Mol. Sci. 19(5). doi: 10.3390/ijms19051501.

33. Chernyshev V.V., Zakharenko A.M., Ugay S.M., Hien T.T., Hai L.H., Kholodov A.S., Burykina T.I., Stratidakis A.K., Mezhuev Ya.O., Tsatsakis A.M., Golokhvast K.S. (2018). Morphologic and chemical composition of particulate matter in motorcycle engine exhaust. Toxicol. Rep. 5, 224–230. doi: 10.1016/j.toxrep.2018.01.003.

32. Engin A.B., Tsatsakis A.M., Tsoukalas D., Engin A. (2018). Do flavanols-rich natural products relieve obesity-related insulin resistance? Food Chem. Toxicol. 112, 157–167. doi: 10.1016/j.fct.2017.12.055.

31. Georgiadis N., Tsarouhas K., Tsitsimpikou C., Vardavas A., Rezaee R., Germanakis I., Tsatsakis A., Stagos D., Kouretas D. (2018).Pesticides and cardiotoxicity. Where do we stand? Sc. Toxicol. .Appl. Pharmacol. 353, 1-14. doi: 10.1016/j.taap.2018.06.004.

30. Golichenari B., Velonia K., Nosrati R., Nezami A., Farokhi-Fard A., Abnous K., Behravan J., Tsatsakis A.M. (2018). Label-free nano-biosensing on the road to tuberculosis detection. Biosens. Bioelectron. 113, 124–135. doi: 10.1016/j.bios.2018.04.059.

29. Hudita A., Galateanu B., Dinescu S., Costache M., Dinischiotu A., Negrei C., Stan M., Tsatsakis A., Nikitovic D., Lupuliasa D., Balanescu A. (2018). In Vitro Effects of Cetylated Fatty Acids Mixture from Celadrin on Chondrogenesis and Inflammation with Impact on Osteoarthritis. Cartilage. doi: 10.1177/1947603518775798.

28. Imtiaz M., Mushtaq M.A., Nawaz M.A., Ashraf M., Rizwan M.S., Mehmood S., Aziz O., Rizwan M., Virk M.S., Shakeel Q., Ijaz R., Androutsopoulos V.P., Tsatsakis A.M., Coleman M.D. (2018). Physiological and anthocyanin biosynthesis genes response induced by vanadium stress in mustard genotypes with distinct photosynthetic activity. Environ. Toxicol. Pharmacol. 62, 20–29. doi: 10.1016/j.etap.2018.06.003.

27. Karzi V., Tzatzarakis M.N., Vakonaki E., Alegakis T., Katsikantami I., Sifakis S., Rizos A., Tsatsakis A.M. (2018). Biomonitoring of bisphenol A, triclosan and perfluorooctanoic acid in hair samples of children and adults. J. Appl. Toxicol. 1–9. doi: 10.1002/jat.3627.

26. Kouretas D., Tsatsakis A., Poulas K. (2018). Editorial: Alternative tobacco products: Toxicology and health issues. Food Chem. Toxicol. 118, 523–525. doi: 10.1016/j.fct.2018.05.056.

25. Mioc M., Pavel I.Z., Ghiulai R., Coricovac D.E., Farcas C., Mihali C.V., Oprean C., Serafim V., Popovici R.A., Dehelean C.A., Shtilman M.I., Tsatsakis A.M., Soica C. (2018). The cytotoxic effects of betulin-conjugated gold nanoparticles as stable formulations in normal and melanoma cells. Front. Pharmacol. 9, 1–16. doi: 10.3389/fphar.2018.00429.

24. Nikitovic D., Berdiaki A., Spyridaki I., Krasanakis T., Tsatsakis A., Tzanakakis G. N. (2018). Proteoglycans-Biomarkers and targets in cancer therapy. Fronti. Endocrinol. 9, 1–8. doi: 10.3389/fendo.2018.00069.

23. Ozcagli E., Kara M.P., Kotil T., Fragkiadaki P., Tzatzarakis M.N., Tsitsimpikou C., Stivaktakis P.D., Tsoukalas D., Spandidos D.A., Tsatsakis A.M., Alpertunga B. (2018). Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging. Int. J. Mol. Med. 42(1), 405–413. doi: 10.3892/ijmm.2018.3644.

22. Taghizadeh S.F., Rezaee R., Davarynejad G., Asili J., Nemati S.H., Goumenou M., Tsakiris I., Tsatsakis A.M., Shirani K., Karimi G. (2018). Risk assessment of exposure to aflatoxin B1 and ochratoxin A through consumption of different Pistachio (Pistacia vera L.) cultivars collected from four geographical regions of Iran. Environ. Toxicol. Pharmacol. 61, 61–66. doi: 10.1016/j.etap.2018.05.010.

21. Tsarouhas, K., Tsitsimpikou, C., Papantoni, X., Lazaridou, D., Koutouzis, M., Mazzaris, S., Rezaee R., Mamoulakis C., Georgoulias P., Nepka C., Rentoukas E., Kyriakides Z., Tsatsakis A., Spandidos D.A., Kouretas, D. (2018). Oxidative stress and kidney injury in trans-radial catheterization. Biomed. Reports. 8(5), 417–425. doi: 10.3892/br.2018.1071.

20. Vardavas A.I., Ozcagli E., Fragkiadaki P., Stivaktakis P.D., Tzatzarakis M.N., Alegakis A.K., Vasilaki F., Kaloudis K., Tsiaoussis J., Kouretas D., Tsitsimpikou C., Carvalho F., Tsatsakis A.M. (2018). The metabolism of imidacloprid by aldehyde oxidase contributes to its clastogenic effect in New Zealand rabbits. Mutat. Res. – Genet. Toxicol. Environ. Mutagen. 829–830, 26–32. doi: 10.1016/j.mrgentox.2018.03.002.

19. Vakonaki E., Tsiminikaki K., Plaitis S., Fragkiadaki P., Tsoukalas D., Katsikantami I., Vaki G., Tzatzarakis M., Spandidos D., Tsatsakis A. (2018) Common mental disorders and association with telomere length (Review), Biomed. Reports. 111–116. doi:10.3892/br.2018.1040.

18. Tzanakakis G., Kavasi R.-M., Voudouri K., Berdiaki A., Spyridaki I., Tsatsakis A., Nikitovic D. (2018) Role of the extracellular matrix in cancer-associated epithelial to mesenchymal transition phenomenon, Dev. Dyn. 247 368–381. doi:10.1002/dvdy.24557.

17. Sokratous M., Dardiotis E., Bellou E., Tsouris Z., Michalopoulou A., Dardioti M., Siokas V., Rikos D., Tsatsakis A., Kovatsi L., Bogdanos D.P., Hadjigeorgiou G.M. (2018) CpG Island Methylation Patterns in Relapsing-Remitting Multiple Sclerosis, J. Mol. Neurosci. 478–484. doi:10.1007/s12031-018-1046-x.

16. Luss A.L., Kulikov P.P., Romme S.B., Andersen C.L., Pennisi C.P., Docea A.O., Kuskov A.N., Velonia K., Mezhuev Y.O., Shtilman M.I., Tsatsakis A.M., Gurevich L. (2018) Nanosized carriers based on amphiphilic poly-N-vinyl-2-pyrrolidone for intranuclear drug delivery, Nanomedicine. nnm-2017-0311. doi:10.2217/nnm-2017-0311.

15. Baltzis D., Meimeti E., Grammatikopoulou M.G., Roustit M., Mavrogonatou E., Kletsas D., Efraimidou S., Manes C., Nikolouzakis T.K., Tsiaoussis J., Tsatsakis A.M., Spandidos D.A., Trakatelli C.-M., Drakoulis N. (2018) Assessment of telomerase activity in leukocytes of type 2 diabetes mellitus patients having or not foot ulcer: Possible correlation with other clinical parameters, Exp. Ther. Med. 15 3420–3424. doi:10.3892/etm.2018.5798.

14. Surichan S., Arroo R.R., Ruparelia K., Tsatsakis A.M., Androutsopoulos V.P. (2018) Nobiletin bioactivation in MDA-MB-468 breast cancer cells by cytochrome P450 CYP1 enzymes, Food Chem. Toxicol. 113 228–235. doi:10.1016/j.fct.2018.01.047.

13. Dardiotis E., Siokas V., Sokratous M., Tsouris Z., Michalopoulou A., Andravizou A., Dastamani M., Ralli S., Vinceti M., Tsatsakis A., Hadjigeorgiou G.M. (2018) Genetic polymorphisms in amyotrophic lateral sclerosis : Evidence for implication in detoxi fi cation pathways of environmental toxicants, Environ. Int. 116 122–135. doi:10.1016/j.envint.2018.04.008.

12. Boda D., Docea A.O., Calina D., Ilie M.A., Caruntu C., Zurac S., Neagu M., Constantin C., Branisteanu D.E., Voiculescu V., Mamoulakis C., Tzanakakis G., Spandidos D.A., Drakoulis N., Tsatsakis A.M. (2018) Human papilloma virus: Apprehending the link with carcinogenesis and unveiling new research avenues (Review), Int. J. Oncol. 52 637–655. doi:10.3892/ijo.2018.4256.

11. Surichan S., Arroo R.R., Tsatsakis A.M., Androutsopoulos V.P.. (2018) Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1–mediated metabolism to the product 4′ hydroxy tangeretin, Toxicol. Vitr. 50 274–284. doi:10.1016/j.tiv.2018.04.001.

10. Seremet O.C., Olaru O.T., Gutu C.M., Nitulescu G.M., Ilie M., Negres S., Zbarcea C.E., Purdel C.N., Spandidos D.A., Tsatsakis A.M., Coleman M.D., Margina D.M.  (2018) Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models, Mol. Med. Rep. 1–7. doi:10.3892/mmr.2018.8795.

9. Yang S.H., Le B., Androutsopoulos V.P., Tsukamoto C., Shin T.S., Tsatsakis A.M., Chung G. (2018) Anti-inflammatory effects of soyasapogenol I-αa via downregulation of the MAPK signaling pathway in LPS-induced RAW 264.7 macrophages, Food Chem. Toxicol. 113 211–217. doi:10.1016/j.fct.2018.01.050.

8. Tsarouhas K., Kioukia-Fougia N., Papalexis P., Tsatsakis A., Kouretas D., Bacopoulou F., Tsitsimpikou C. (2018) Use of nutritional supplements contaminated with banned doping substances by recreational adolescent athletes in Athens, Greece, Food Chem. Toxicol. 115 447–450. doi:10.1016/j.fct.2018.03.043.

7. Nikolouzakis T., Vassilopoulou L., Fragkiadaki P., Mariolis Sapsakos T., Papadakis G., Spandidos D., Tsatsakis A., Tsiaoussis J. (2018) Improving diagnosis, prognosis and prediction by using biomarkers in CRC patients (Review), Oncol. Rep. 2455–2472. doi:10.3892/or.2018.6330.

6. Docea A.O., Gofita E., Goumenou M., Calina D., Rogoveanu O., Varut M., Olaru C., Kerasioti E., Fountoucidou P., Taitzoglou I., Zlatian O., Rakitskii V.N., Hernandez A.F., Kouretas D., Tsatsakis A. (2018) Six months exposure to a real life mixture of 13 chemicals’ below individual NOAELs induced non monotonic sex-dependent biochemical and redox status changes in rats, Food Chem. Toxicol. 115 470–481. doi:10.1016/j.fct.2018.03.052.

5. Kerasioti E., Stagos D., Tsatsakis A.M., Spandidos D.A., Taitzoglou I., Kouretas D. (2018) Effects of sheep/goat whey protein dietary supplementation on the redox status of rats, Mol. Med. Rep. 17 5774–5781. doi:10.3892/mmr.2018.8622.

4. Kalliora C., Mamoulakis C., Vasilopoulos E., Stamatiades G.A., Kalafati L., Barouni R., Karakousi T., Abdollahi M., Tsatsakis A. (2018) Association of pesticide exposure with human congenital abnormalities, Toxicol. Appl. Pharmacol. 346 58–75. doi:10.1016/j.taap.2018.03.025.

3. Maturu P., Wei-Liang Y., Androutsopoulos V.P., Jiang W., Wang L., Tsatsakis A.M., Couroucli X.I. (2018) Quercetin attenuates the hyperoxic lung injury in neonatal mice: Implications for Bronchopulmonary dysplasia (BPD), Food Chem. Toxicol. 114 23–33. doi:10.1016/j.fct.2018.02.026.

2. Pinzaru, I., Coricovac, D., Dehelean, C., Moacă, E. A., Mioc, M., Baderca, F., Sizemore, I., Brittle, S., Marti, D., Calina, C.D., Tsatsakis, A.M., Şoica, C. (2018). Stable PEG-coated silver nanoparticles – A comprehensive toxicological profile. Food and Chemical Toxicology, 111(December 2017), 546–556. http://doi.org/10.1016/j.fct.2017.11.051

1. Veremchuk, L. V., Tsarouhas, K., Vitkina, T. I., Mineeva, E. E., Gvozdenko, T. A., Antonyuk, M. V., Rakitskii, V.N., Sidletskaya, C.A., Tsatsakis, A.M., Golokhvast, K. S. (2018). Impact evaluation of environmental factors on respiratory function of asthma patients living in urban territory. Environmental Pollution, 235, 489–496.




55. Petrakis, D., Vassilopoulou, L., Mamoulakis, C., Psycharakis, C., Anifantaki, A., Sifakis, S., … Tsatsakis, A. M. (2017). Endocrine disruptors leading to obesity and related diseases. International Journal of Environmental Research and Public Health, 14(10), 1–18. http://doi.org/10.3390/ijerph14101282

54. Zakharenko, A. M., Engin, A. B., Chernyshev, V. V., Chaika, V. V., Ugay, S. M., Rezaee, R., Karimi, G., Drozd, V. A., Nikitina, A. V., Solomennik, S. F., Kudryavkina, O. R., Xin, L., Wenpeng, Y., Tzatzarakis, M., Tsatsakis, A. M. Golokhvast, K. S. (2017). Basophil mediated pro-allergic inflammation in vehicle-emitted particles exposure. Environmental Research, 152, 308–314. ttp://doi.org/10.1016/j.envres.2016.10.031

53. Mytilinaiou, M., Nikitovic, D., Berdiaki, A., Papoutsidakis, A., Papachristou, D. J., Tsatsakis, A., & Tzanakakis, G. N. (2017). IGF-I regulates HT1080 fibrosarcoma cell migration through a syndecan-2/Erk/ezrin signaling axis. Experimental Cell Research, 361(1), 9–18. http://doi.org/10.1016/j.yexcr.2017.09.035

52. Costa, C., Tsatsakis, A., Mamoulakis, C., Teodoro, M., Briguglio, G., Caruso, E., … Fenga, C. (2017). Current evidence on the effect of dietary polyphenols intake on chronic diseases. Food and Chemical Toxicology, 110(August), 286–299. http://doi.org/10.1016/j.fct.2017.10.023

51. Blazaki, S., Tsika, C., Tzatzarakis, M., Naoumidi, E., Tsatsakis, A., Tsatsanis, C., & Tsilimbaris, M. K. (2017). Pharmacokinetics and efficacy of intraocular flurbiprofen. Graefe’s Archive for Clinical and Experimental Ophthalmology, 255(12), 2375–2380. http://doi.org/10.1007/s00417-017-3812-9

50. Ungureanu, A., Zlatian, O., Mitroi, G., Drocaş, A., Ţîrcã, T., Cǎlina, D., Dehelean, C., Docea, A. O., Izotov, B. N., Rakitskii, V. N., Cioboata, R., Spandidos, D. A., Tsatsakis, A. M., Gǎman, A. (2017). Staphylococcus aureus colonisation in patients from a primary regional hospital. Molecular Medicine Reports, 16(6), 8771–8780. http://doi.org/10.3892/mmr.2017.7746

49. Caunii, A., Oprean, C., Cristea, M., Ivan, A., Danciu, C., Tatu, C., Paunescu, V., Marti, D., Tzanakakis, G., Spandidos, D. A., Tsatsakis, A., Susan, R., Soica, C., Avram, S. (2017). Effects of ursolic and oleanolic on SK-MEL-2 melanoma cells: In vitro and in vivo assays. International Journal of Oncology, 51(6), 1651–1660. http://doi.org/10.3892/ijo.2017.4160

48. Papadopoulou, A., Petrotos, K., Stagos, D., Gerasopoulos, K., Maimaris, A., Makris, H., Kafantaris, I., Makri, S., Kerasioti, E., Halabalaki, M., Brieudes, V., Ntasi, G., Kokkas, S., Tzimas, P., Goulas, P., Zakharenko, A. M., Golokhvast, K.S., Tsatsakis, A., Kouretas, D. (2017). Enhancement of Antioxidant Mechanisms and Reduction of Oxidative Stress in Chickens after the Administration of Drinking Water Enriched with Polyphenolic Powder from Olive Mill Waste Waters. Oxidative Medicine and Cellular Longevity, 2017. http://doi.org/10.1155/2017/8273160

47. Wilsher, N. E., Arroo, R. R., Matsoukas, M. T., Tsatsakis, A. M., Spandidos, D. A., & Androutsopoulos, V. P. (2017). Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells. Food and Chemical Toxicology, 110(October), 383–394. http://doi.org/10.1016/j.fct.2017.10.051

46. Sayapina, N. V., Batalova, T. A., Sergievich, A. A., Shtarberg, M. A., Borodin, E. A., Khoroshikh, P. P., Chaika, V. V., Kodintsev, V. V., Vedyagin, A. A., Mishakov, I. V., Vakis, A., Henrich-Noack, P., Tsatsakis, A. M., Engin, A. B., Golokhvast, K. (2017). Oral application of carbon nanofibers in rats increases blood concentration of IL6 and IL10 and decreases locomotor activity. Environmental Toxicology and Pharmacology, 50, 183–191. http://doi.org/10.1016/j.etap.2017.01.015

45. Vucinic, S., Antonijevic, B., Tsatsakis, A. M., Vassilopoulou, L., Docea, A. O., Nosyrev, A. E., … Brkic, D. (2017). Environmental exposure to organophosphorus nerve agents. Environmental Toxicology and Pharmacology, 56(June), 163–171. http://doi.org/10.1016/j.etap.2017.09.004

44. Balmuri, S. R., Selvaraj, U., Kumar, V. V., Anthony, S. P., Tsatsakis, A. M., Golokhvast, K. S., & Raman, T. (2017). Effect of surfactant in mitigating cadmium oxide nanoparticle toxicity: Implications for mitigating cadmium toxicity in environment. Environmental Research, 152(July 2016), 141–149. http://doi.org/10.1016/j.envres.2016.10.005

43. Katsarou, M. S., Karakonstantis, K., Demertzis, N., Vourakis, E., Skarpathioti, A., Nosyrev, A. E., Tsatsakis, A., Kalogridis, T., Drakoulis, N. (2017). Effect of single-nucleotide polymorphisms in ADH1B, ADH4, ADH1C, OPRM1, DRD2, BDNF, and ALDH2 genes on alcohol dependence in a Caucasian population. Pharmacology Research and Perspectives, 5(4), 1–10. http://doi.org/10.1002/prp2.326

42. Vinceti, M., Violi, F., Tzatzarakis, M., Mandrioli, J., Malagoli, C., Hatch, E. E., … Tsatsakis, A. (2017). Pesticides, polychlorinated biphenyls and polycyclic aromatic hydrocarbons in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a case-control study. Environmental Research, 155(February), 261–267. http://doi.org/10.1016/j.envres.2017.02.025

41. Radu, I.-C., Hudita, A., Zaharia, C., Stanescu, P. O., Vasile, E., Iovu, H., Stan, M., Ginghina, O., Galateanu, B., Costache, M., Langguth, P., Tsatsakis, A., Velonia, K.,  Negrei, C. (2017). Poly(HydroxyButyrate-co-HydroxyValerate) (PHBHV) Nanocarriers for Silymarin Release as Adjuvant Therapy in Colo-rectal Cancer. Frontiers in Pharmacology, 8, 508. http://doi.org/10.3389/fphar.2017.00508

40. Cioboată, R., Găman, A., Traşcă, D., Ungureanu, A., Docea, A., Tomescu, P., Gherghina, F., Arsene, A., Badiu, C., Tsatsakis, A., Spandidos, D., Drakoulis, N., Calina, D. (2017). Pharmacological management of non-alcoholic fatty liver disease: Atorvastatin versus pentoxifylline. Experimental and Therapeutic Medicine, 2375–2381. http://doi.org/10.3892/etm.2017.4256

39. Vardavas, C. I., Girvalaki, C., Filippidis, F. T., Oder, M., Kastanje, R., de Vries, I., Scholtens, L., Annas, A., Plackova, S., Turk, R., Gruzdyte, L., Rato, F., Genser, D., Schiel, H., Balázs, A., Donohoe, E., Vardavas, A., Tzatzarakis, M.N., Tsatsakis, A.M., Behrakis, P. K. (2017). Characteristics and outcomes of e-cigarette exposure incidents reported to 10 European Poison Centers: a retrospective data analysis. Tobacco Induced Diseases, 15(1), 36. http://doi.org/10.1186/s12971-017-0141-z

38. Nezami, A., Nosrati, R., Golichenari, B., Rezaee, R., Chatzidakis, G. I., Tsatsakis, A. M., & Karimi, G. (2017). Nanomaterial-based aptasensors and bioaffinity sensors for quantitative detection of 17β-estradiol. TrAC - Trends in Analytical Chemistry, 94, 95–105. http://doi.org/10.1016/j.trac.2017.07.003

37. Hernández, A. F., & Tsatsakis, A. M. (2017). Human exposure to chemical mixtures: Challenges for the integration of toxicology with epidemiology data in risk assessment. Food and Chemical Toxicology, 103, 188–193. http://doi.org/10.1016/j.fct.2017.03.012

36. Nitipir, C., Niculae, D., Orlov, C., Barbu, M., Popescu, B., Popa, A., Stoian Pantea, A., Stanciu, A., Galateanu, B., Ginghina, O., Papadakis, G., Izotov, B., Spandidos, D., Tsatsakis, A., Negrei, C. (2017). Update on radionuclide therapy in oncology (Review). Oncology Letters, 7011–7015. http://doi.org/10.3892/ol.2017.7141

35. Tzanakakis, G., Kavasi, R.-M., Voudouri, K., Berdiaki, A., Spyridaki, I., Tsatsakis, A., & Nikitovic, D. (2017). The role of the extracellular matrix in cancer-associated epithelial to mesenchymal transition phenomenon. Developmental Dynamics, 1–47. http://doi.org/10.1002/dvdy.24557

34. Tsamouri, M.-M., Rapti, M., Kouka, P., Nepka, C., Tsarouhas, K., Soumelidis, A., Koukoulis, G., Tsatsakis, A., Kouretas, D., Tsitsimpikou, C. (2017). Histopathological evaluation and redox assessment in blood and kidney tissues in a rabbit contrast-induced nephrotoxicity model. Food and Chemical Toxicology, 108, 186–193. http://doi.org/10.1016/j.fct.2017.07.058

33. Serafim, V., Shah, A., Puiu, M., Andreescu, N., Coricovac, D., Nosyrev, A., Spandidos, D., Tsatsakis, A., Dehelean, C., Pinzaru, I. (2017). Classification of cancer cell lines using matrix-assisted laser desorption/ionization time‑of‑flight mass spectrometry and statistical analysis. International Journal of Molecular Medicine, 1–9. http://doi.org/10.3892/ijmm.2017.3083

32. Tsatsakis AM, Lash LH. (2017). Toxicology: The basic science for human well-being and environmental health. Toxicol. Reports 1–2; doi:10.1016/j.toxrep.2017.01.002.

31. Ruszkiewicz JA, Pinkas A, Ferrer B, Peres T V., Tsatsakis A, Aschner M. (2017). Neurotoxic effect of active ingredients in sunscreen products, a contemporary review. Toxicol. Reports 4:245–259; doi:10.1016/j.toxrep.2017.05.006.

30. Fenga C, Gangemi S, Teodoro M, Rapisarda V, Golokhvast K, Docea AO, Tsatsakis AM, Costa C. (2017). 8-Hydroxydeoxyguanosine as a biomarker of oxidative DNA damage in workers exposed to low-dose benzene. Toxicol. Reports 4:291–295; doi:10.1016/j.toxrep.2017.05.008.

29. Kerasioti E, Terzopoulou Z, Komini O, Kafantaris I, Makri S, Stagos D, Gerasopoulos K, Anisimov N.Y, Tsatsakis AM, Kouretas D. (2017). Tissue specific effects of feeds supplemented with grape pomace or olive oil mill wastewater on detoxification enzymes in sheep. Toxicol. Reports 4:364–372; doi:10.1016/j.toxrep.2017.06.007.

28. Hashemzaei M., Delarami Far A., Yari A., Heravi R., Tabrizian K., Taghdisi S., Sadegh S., Tsarouhas K., Kouretas D., Tzanakakis G., Nikitovic D., Anisimov N., Spandidos D., Tsatsakis A., Rezaee R. (2017). Anticancer and apoptosis inducing effects of quercetin in vitro and in vivo. Oncology Reports, 38 (2): 819–828. doi:10.3892/or.2017.5766.

27. Yang S., Tsatsakis A., Tzanakakis G., Kim H., Le B., Sifaki M., Spandidos D., Tsukamoto C., Golokhvast K., Izotov B., Chung G. (2017). Soyasaponin Ag inhibits α MSH induced melanogenesis in B16F10 melanoma cells via the downregulation of TRP 2. International Journal of Molecular Medicine, 40(3): 631-636. doi:10.3892/ijmm.2017.3061.

26. Lupu M., Caruntu A., Caruntu C., Papagheorghe L., Ilie M., Voiculescu V., Boda D., Carolina C., Tanase C., Sifaki M., Drakoulis N., Mamoulakis C., Tzanakakis G., Neagu M., Spandidos D., Izotov B., Tsatsakis A. (2017). Neuroendocrine factors: The missing link in non melanoma skin cancer (Review). Oncology Reports, 38(3):1327-1340. doi:10.3892/or.2017.5817.

25. Kouka P., Priftis A., Stagos D., Angelis A., Stathopoulos P., Xinos N., Skaltsounis A., Mamoulakis C., Tsatsakis A., Spandidos D., Kouretas D. (2017). Assessment of the antioxidant activity of an olive oil total polyphenolic fraction and hydroxytyrosol from a Greek Olea europea variety in endothelial cells and myoblasts. International Journal of Molecular Medicine, 40:703-712 doi:10.3892/ijmm.2017.3078.

24. Nestoros J.N., Vakonaki E., Tzatzarakis M.N., Alegakis A., Skondras M.D., Tsatsakis A.M. Long lasting effects of chronic heavy cannabis abuse, Am. J. Addict. (2017) 335–342.

23. Kuskov A.N., Kulikov P.P., Goryachaya A. V., Tzatzarakis M.N., Docea A.O., Velonia K., Shtilman M.I., Tsatsakis A.M. Amphiphilic poly-N-vinylpyrrolidone nanoparticles as carriers for non-steroidal, anti-inflammatory drugs: In vitro cytotoxicity and in vivo acute toxicity study, Nanomedicine Nanotechnology, Biol. Med. 13 (2017) 1021–1030.

22. Alamolhodaei NS, Tsatsakis AM, Ramezani M, Hayes AW, Karimi G. Resveratrol as MDR reversion molecule in breast cancer: An overview. Food Chem Toxicol. 2017 May;103:223-232.

21. Vinceti M, Filippini T, Cilloni S, Bargellini A, Vergoni AV, Tsatsakis A, Ferrante M. Health risk assessment of environmental selenium: Emerging evidence and challenges (Review). Mol Med Rep. 2017 May;15(5):3323-3335

20. Tsatsakis AM, Nawaz MA, Kouretas D, Balias G, Savolainen K, Tutelyan VA, Golokhvast KS, Lee JD, Yang SH, Chung G. Environmental impacts of genetically modified plants: A review. Environ Res. 2017 Mar 27 [IN PRESS]

19. Tzatzarakis MN, Vakonaki E, Moti S, Alegakis A, Tsitsimpikou C, Tsakiris I,  Goumenou M, Nosyrev AE, Rizos AK, Tsatsakis AM. Quantification of 4-Methylimidazole in soft drinks, sauces and vinegars of Greek market using two liquid chromatography techniques. Food Chem. Toxicol. 2017 (in press).

18. Karaulov A V., Mikhaylova I V., Smolyagin AI, Boev VM, Kalogeraki A, Tsatsakis AM, Engin AB. The immunotoxicological pattern of subchronic and chronic benzene exposure in rats. Toxicol. Lett. 2017;275:1–5.

17. Wojciechowski V V., Calina D, Tsarouhas K, Pivnik A V., Sergievich AA, Kodintsev V V., Filatova EA, Ozcagli E, Docea AO, Arsene AL, Gofita E, Tsitsimpikou C, Tsatsakis AM, Golokhvast KS. A guide to acquired vitamin K coagulophathy diagnosis and treatment: the Russian perspective. DARU J. Pharm. Sci. 2017; 25:10.

16. Cioboată R., Găman A., Traşcă D., Ungureanu A., Docea A., Tomescu P., Gherghina F., Arsene A., Badiu C., Tsatsakis A., Spandidos D., Drakoulis N., Călina D. Pharmacological management of non-alcoholic fatty liver disease: Atorvastatin versus pentoxifylline, Exp. Ther. Med. (2017) 2375–2381.

15. Coricovac D.-E., Moacă E.-A., Pinzaru I., Cîtu C., Soica C., Mihali C.-V., Păcurariu C., Tutelyan V.A., Tsatsakis A., Dehelean C.-A. Biocompatible Colloidal Suspensions Based on Magnetic Iron Oxide Nanoparticles: Synthesis, Characterization and Toxicological Profile, Front. Pharmacol. 8 (2017) 154.

14. Mioc M, Soica C, Bercean V, Avram S, Balan Porcarasu M, Coricovac D, Ghiulai R, Muntean D, Andrica F, Dehelean C, Spandidos D, Tsatsakis AM, Kurunczi L. Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-triazole derivatives with antibacterial and antiproliferative activity. Int. J. Oncol. 2017 Apr; 50(4): 1175–1183.

13. Taghizadeh, S. F., Davarynejad, G., Asili, J., Nemati, S. H., Rezaee, R., Goumenou, M., … Karimi, G. (2017). Health risk assessment of heavy metals via dietary intake of five pistachio ( Pistacia vera L.) cultivars collected from different geographical sites of Iran. Food and Chemical Toxicology, 107(Pt A), 99–107. http://doi.org/10.1016/j.fct.2017.06.035

12. Engin, A. B., Nikitovic, D., Neagu, M., Henrich-Noack, P., Docea, A. O., Shtilman, M. I., … Tsatsakis, A. M. (2017). Mechanistic understanding of nanoparticles? interactions with extracellular matrix: the cell and immune system. Particle and Fibre Toxicology, 14(1), 22. http://doi.org/10.1186/s12989-017-0199-z

11. Tsatsakis, A. M., Nawaz, M. A., Tutelyan, V. A., Golokhvast, K. S., Kalantzi, O.-I., Chung, D. H., … Chung, G. (2017). Impact on environment, ecosystem, diversity and health from culturing and using GMOs as feed and food. Food and Chemical Toxicology, 107, 108–121. http://doi.org/10.1016/j.fct.2017.06.033

10. Mamoulakis, C., Tsarouhas, K., Fragkiadoulaki, I., Heretis, I., Wilks, M. F., Spandidos, D. A., … Tsatsakis, A. (2017). Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies. Pharmacology & Therapeutics. http://doi.org/10.1016/j.pharmthera.2017.06.009

9. Mamoulakis, C., Avgenakis, G., Gkatzoudi, C., Duyker, G., Zisis, I., Heretis, I., … Tzonou, A. (2017). Seasonal trends in the prevalence of hypospadias: Aetiological implications. Experimental and Therapeutic Medicine, 13(6), 2960–2968. http://doi.org/10.3892/etm.2017.4323

8. Vassilopoulou, L., Psycharakis, C., Petrakis, D., Tsiaoussis, J., & Tsatsakis, A. M. (2017). Obesity, Persistent Organic Pollutants and Related Health Problems. In Advances in experimental medicine and biology (Vol. 960, pp. 81–110). http://doi.org/10.1007/978-3-319-48382-5_4

7. Negrei, C., Galateanu, B., Stan, M., Balalau, C., Dumitru, M. L. B., Ozcagli, E., … Tsatsakis, A. (2017). Worldwide legislative challenges related to psychoactive drugs. DARU Journal of Pharmaceutical Sciences, 25(1), 14. http://doi.org/10.1186/s40199-017-0180-2

6. Renieri, E. A., Sfakianakis, D. G., Alegakis, A. A., Safenkova, I. V., Buha, A., Matovi?, V., … Tsatsakis, A. M. (2017). Nonlinear responses to waterborne cadmium exposure in zebrafish. An in vivo study. Environmental Research, 157, 173–181. http://doi.org/10.1016/j.envres.2017.05.021

5. Spanidis, Y., Priftis, A., Stagos, D., Stravodimos, G., Leonidas, D., Spandidos, D., … Kouretas, D. (2017). Oxidation of human serum albumin exhibits inter-individual variability after an ultra-marathon mountain race. Experimental and Therapeutic Medicine, 13(5), 2382–2390. http://doi.org/10.3892/etm.2017.4268

4. Avram, S., Coricovac, D., Pavel, I., Pinzaru, I., Ghiulai, R., Baderca, F., … Dehelean, C. (2017). Standardization of A375 human melanoma models on chicken embryo chorioallantoic membrane and Balb/c nude mice. Oncology Reports, 38(1), 89–99. http://doi.org/10.3892/or.2017.5658

3. Tsatsakis, A., Kouretas, D., Tzatzarakis, M., Stivaktakis, P., Tsarouhas, K., Golokhvast, K., … Tsitsimpikou, C. (2017). Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach. Human & Experimental Toxicology, 36(6), 554–564. http://doi.org/10.1177/0960327116681652

2. Tsoukalas, D., Alegakis, A., Fragkiadaki, P., Papakonstantinou, E., Nikitovic, D., Karataraki, A., … Tsatsakis, A. (2017). Application of metabolomics: Focus on the quantification of organic acids in healthy adults. International Journal of Molecular Medicine, 40(1), 112–120. http://doi.org/10.3892/ijmm.2017.2983

1. Engin A, Engin E, Golokhvast K, Spandidos D, Tsatsakis AM. Glutamate mediated effects of caffeine and interferon γ on mercury-induced toxicity.International Journal of Molecular Medicine 2017; 39:1215–1223



39. Călina D, Docea AO, Rosu L, Zlatian O, Rosu AF, Anghelina F, Rogoveanu O, Arsene AL, Nicolae AC, Drăgoi CM, Tsiaoussis J, Tsatsakis AM, Spandidos DA, Drakoulis N, Gofita E. Antimicrobial resistance development following surgical site infections. Mol Med Rep. 2017 Feb;15(2):681-688.

38. Tzatzarakis MN, Alegakis AK, Kavvalakis MP, Vakonaki E, Stivaktakis PD, Kanaki K, Vardavas AI, Barbounis EG, Tsatsakis AM. Comparative Evaluation of Drug Deposition in Hair Samples Collected from Different Anatomical Body Sites. J Anal Toxicol. 2016 Dec 15. [Epub ahead of print]

37. Vakonaki E, Tsarouhas K, Spandidos DA, Tsatsakis AM. Complex interplay of DNA damage, DNA repair genes, and oxidative stress in coronary artery disease. Anatol J Cardiol. 2016 Dec;16(12):939.

36. Tsitsimpikou C, Tsarouhas K, Spandidos DA, Tsatsakis AM. Detection of stanozolol in the urine of athletes at a pg level: The possibility of passive exposure. Biomed Rep. 2016 Dec;5(6):665-666.

35. Zakharenko AM, Engin AB, Chernyshev VV, Chaika VV, Ugay SM, Rezaee R, Karimi G, Drozd VA, Nikitina AV, Solomennik SF, Kudryavkina OR, Xin L, Wenpeng Y, Tzatzarakis M, Tsatsakis AM, Golokhvast KS. Basophil mediated pro-allergic inflammation in vehicle-emitted particles exposure. Environ Res. 2017 Jan;152:308-314.

34. Ianoşi S, Ianoşi G, Neagoe D, Ionescu O, Zlatian O, Docea AO, Badiu C, Sifaki M, Tsoukalas D, Tsatsakis AM, Spandidos DA, Călina D. Age-dependent endocrine disorders involved in the pathogenesis of refractory acne in women. Mol Med Rep. 2016 Dec;14(6):5501-5506.

33. Kuskov AN, Kulikov PP, Goryachaya AV, Tzatzarakis MN, Docea AO, Velonia K, Shtilman MI, Tsatsakis AM. Amphiphilic poly-N-vinylpyrrolidone nanoparticles as carriers for non-steroidal, anti-inflammatory drugs: In vitro cytotoxicity and in vivo acute toxicity study. Nanomedicine. 2016 Nov 22;13(3):1021-1030.

32. Tzatzarakis MN, Karzi V, Vakonaki E, Goumenou M, Kavvalakis M, Stivaktakis P, Tsitsimpikou C, Tsakiris I, Rizos AK, Tsatsakis AM. Bisphenol A in soft drinks and canned foods and data evaluation. Food Addit Contam Part B Surveill. 2016 Dec 11:1-6. [Epub ahead of print]

31. Voudouri K, Nikitovic D, Berdiaki A, Papachristou DJ, Tsiaoussis J, Spandidos DA, Tsatsakis AM, Tzanakakis GN. Heparin regulates B6FS cell motility through a FAK/actin cytoskeleton axis. Oncol Rep. 2016 Aug 30. [Epub ahead of print]

30. Shishatskaya EI, Nikitovic D, Vasilievich AS, Tzanakakis GN, Tsatsakis AM, Menzianova NG. Short-term culture of monocytes as an in vitro evaluation system for bionanomaterials designated for medical use. Food Chem Toxicol. 2016 Aug 21;96:302-308.

29. Kuskov AN, Kulikov PP, Shtilman MI, Rakitskii VN, Tsatsakis AM. Amphiphilic poly-N-vynilpyrrolidone nanoparticles: Cytotoxicity and acute toxicity study. Food Chem Toxicol. 2016 Aug 15;96:273-279.

28. Tsatsakis AM, Docea AO, Tsitsimpikou C. New challenges in risk assessment of chemicals when simulating real exposure scenarios; simultaneous multi-chemicals' low dose exposure. Food Chem Toxicol. 2016 Aug 8;96:174-176.

27. Nikitovic D, Kavasi RM, Berdiaki A, Papachristou DJ, Tsiaoussis J, Spandidos DA, Tsatsakis AM, Tzanakakis GN. Parathyroid hormone/parathyroid hormone-related peptide regulate osteosarcoma cell functions: Focus on the extracellular matrix (Review). Oncol Rep. 2016 Aug 1. [Epub ahead of print]

26. Hashemzaei M, Barani AK, Iranshahi M, Rezaee R, Tsarouhas K, Tsatsakis AM, Wilks MF, Tabrizian K. Effects of resveratrol on carbon monoxide-induced cardiotoxicity in rats. Environ Toxicol Pharmacol. 2016 Jul 19;46:110-115.

25. Negrei C, Hudita A, Ginghina O, Galateanu B, Voicu SN, Stan M, Costache M, Fenga C, Drakoulis N, Tsatsakis AM. Colon Cancer Cells Gene Expression Signature As Response to 5- Fluorouracil, Oxaliplatin, and Folinic Acid Treatment. Front Pharmacol. 2016 Jun 23;7:172.

24. Neagu M, Piperigkou Z, Karamanou K, Engin AB, Docea AO, Constantin C, Negrei C, Nikitovic D, Tsatsakis A. Protein bio-corona: critical issue in immune nanotoxicology. Arch Toxicol. 2016 Jul 20. [Epub ahead of print] Review.

23. Dehelean CA, Soica C, Pinzaru I, Coricovac D, Danciu C, Pavel I, Borcan F, Spandidos DA, Tsatsakis AM, Baderca F. Sex differences and pathology status correlated to the toxicity of some common carcinogens in experimental skin carcinoma. Food Chem Toxicol. 2016 Sep;95:149-58.

22. Tsitsimpikou C, Vasilaki F, Tsarouhas K, Fragkiadaki P, Tzardi M, Goutzourelas N, Nepka C, Kalogeraki A, Heretis I, Epitropaki Z, Kouretas D, Tsatsakis AM. Nephrotoxicity in rabbits after long-term nandrolone decanoate administration. Toxicol Lett. 2016 Jun 23;259:21-27.

21. Wilks MF, Blaauboer BJ, Schulte-Hermann R, Wallace HM, Galli CL, Haag-Grönlund M, Matović V, Teixeira JP, Zilliacus J, Basaran N, Bonefeld-Jørgensen EC, Bourrinet P, Brueller W, Claude N, Miranda JP, Gundert-Remy U, Håkansson H, Kovatsi L, Liesivuori J, Lindeman B, Lison D, Leconte I, Martínez-López E, Murias M, Michel C, Scheepers PT, Stanley L, Tsatsakis A. The European Registered Toxicologist (ERT): Current status and prospects for advancement. Toxicol Lett. 2016 Jun 22. pii: S0378-4274(16)30163-1.

20. Vardavas AI, Stivaktakis PD, Tzatzarakis MN, Fragkiadaki P, Vasilaki F, Tzardi M, Datseri G, Tsiaoussis J, Alegakis AK, Tsitsimpikou C, Rakitskii VN, Carvalho F, Tsatsakis AM. Long-term exposure to cypermethrin and piperonyl butoxide cause liver and kidney inflammation and induce genotoxicity in New Zealand white male rabbits. Food Chem Toxicol. 2016 Aug;94:250-9.

19. Katsarou MS, Latsi R, Papasavva M, Demertzis N, Kalogridis T, Tsatsakis AM, Spandidos DA, Drakoulis N. Population-based analysis of the frequency of HFE gene polymorphisms: Correlation with the susceptibility to develop hereditary hemochromatosis. Mol Med Rep. 2016 Jul;14(1):630-6.

18. Fragkiadaki P, Tsoukalas D, Fragkiadoulaki I, Psycharakis C, Nikitovic D, Spandidos DA, Tsatsakis AM. Telomerase activity in pregnancy complications (Review). Mol Med Rep. 2016 Jul;14(1):16-21.

17. Wallace H, Roberts R, Corsini E, Bonefeld-Jorgensen E, Orhan H, Mach M, Weiser T, Carvalho F, Iscan M, Tsatsakis A. Toxicology as an academic discipline in European Universities. Toxicol Lett. 2016 Jul 8;254:63.

16. Zurac S, Neagu M, Constantin C, Cioplea M, Nedelcu R, Bastian A, Popp C, Nichita L, Andrei R, Tebeica T, Tanase C, Chitu V, Caruntu C, Ghita M, Popescu C, Boda D, Mastalier B, Maru N, Daha C, Andreescu B, Marinescu I, Rebosapca A, Staniceanu F, Negroiu G, Ion DA, Nikitovic D, Tzanakakis GN, Spandidos DA, Tsatsakis AM. Variations in the expression of TIMP1, TIMP2 and TIMP3 in cutaneous melanoma with regression and their possible function as prognostic predictors. Oncol Lett. 2016 May;11(5):3354-3360.

15. Ghita MA, Caruntu C, Rosca AE, Kaleshi H, Caruntu A, Moraru L, Docea AO, Zurac S, Boda D, Neagu M, Spandidos DA, Tsatsakis AM. Reflectance confocal microscopy and dermoscopy for in vivo, non-invasive skin imaging of superficial basal cell carcinoma. Oncol Lett. 2016 May;11(5):3019-3024.

14. Koureas M, Karagkouni F, Rakitskii V, Hadjichristodoulou C, Tsatsakis A, Tsakalof A. Serum levels of organochlorine pesticides in the general population of Thessaly, Greece, determined by HS-SPME GC-MS method. Environ Res. 2016 Jul;148:318-21.

13. Negrei C, Bojinca V, Balanescu A, Bojinca M, Baconi D, Spandidos DA, Tsatsakis AM, Stan M. Management of rheumatoid arthritis: Impact and risks of various therapeutic approaches. Exp Ther Med. 2016 Apr;11(4):1177-1183.

12. Galateanu B, Hudita A, Negrei C, Ion RM, Costache M, Stan M, Nikitovic D, Hayes AW, Spandidos DA, Tsatsakis AM, Ginghina O. Impact of multicellular tumor spheroids as an in vivo like tumor model on anticancer drug response. Int J Oncol. 2016 Jun;48(6):2295-302.

11. Spanidis Y, Mpesios A, Stagos D, Goutzourelas N, Bar-Or D, Karapetsa M, Zakynthinos E, Spandidos DA, Tsatsakis AM, Leon G, Kouretas D. Assessment of the redox status in patients with metabolic syndrome and type 2 diabetes reveals great variations. Exp Ther Med. 2016 Mar;11(3):895-903.

10. Neagu M, Caruntu C, Constantin C, Boda D, Zurac S, Spandidos DA, Tsatsakis AM. Chemically induced skin carcinogenesis: Updates in experimental models (Review). Oncol Rep. 2016 May;35(5):2516-28.

9. Piperigkou Z, Karamanou K, Engin AB, Gialeli C, Docea AO, Vynios DH, Pavão MS, Golokhvast KS, Shtilman MI, Argiris A, Shishatskaya E, Tsatsakis AM. Emerging aspects of nanotoxicology in health and disease: From agriculture and food sector to cancer therapeutics. Food Chem Toxicol. 2016 May;91:42-57.

8. Knipe DW, Jayasumana C, Siribaddana S, Priyadarshana C, Pearson M, Gunnell D, Metcalfe C, Tzatzarakis MN, Tsatsakis AM. Feasibility of hair sampling to assess levels of organophosphate metabolites in rural areas of Sri Lanka. Environ Res. 2016 May;147:207-11.

7. Memariani T, Hosseini T, Kamali H, Mohammadi A, Ghorbani M, Shakeri A, Spandidos DA, Tsatsakis AM, Shahsavand S. Evaluation of the cytotoxic effects of Cyperus longus extract, fractions and its essential oil on the PC3 and MCF7 cancer cell lines. Oncol Lett. 2016 Feb;11(2):1353-1360.

6. Raman V, Suresh S, Savarimuthu PA, Raman T, Tsatsakis AM, Golokhvast KS, Vadivel VK. Synthesis of Co3O4 nanoparticles with block and sphere morphology, and investigation into the influence of morphology on biological toxicity. Exp Ther Med. 2016 Feb;11(2):553-560.

5. Spanidis Y, Goutzourelas N, Stagos D, Mpesios A, Priftis A, Bar-Or D, Spandidos DA, Tsatsakis AM, Leon G, Kouretas D. Variations in oxidative stress markers in elite basketball players at the beginning and end of a season. Exp Ther Med. 2016 Jan;11(1):147-153.

4. Fenga C, Gangemi S, Giambò F, Tsitsimpikou C, Golokhvast K, Tsatsakis A, Costa C. Low-dose occupational exposure to benzene and signal transduction pathways involved in the regulation of cellular response to oxidative stress. Life Sci. 2016 Jan 14. pii: S0024-3205(15)30118-1.

3. Costa C, Ozcagli E, Gangemi S, Schembri F, Giambò F, Androutsopoulos V, Tsatsakis A, Fenga C. Molecular biomarkers of oxidative stress and role of dietary factors in gasoline station attendants. Food Chem Toxicol. 2016 Jan 29;90:30-35.

2. Rezaee M.A., Mohammadpour A.H., Imenshahidi M., Mahmoudi M., Sankian M., Tsarouhas K., Tsakalof A., Tsatsakis A.M., Moallem S.A. Protective effect of erythropoietin on myocardial apoptosis in rats exposed to carbon monoxide, Life Sci. 148 (2016) 118–124.

1. Stivaktakis PD, Kavvalakis MP, Tzatzarakis MN, Alegakis AK, Panagiotakis MN, Fragkiadaki P, Vakonaki E, Ozcagli E, Hayes WA, Rakitskii VN, Tsatsakis AM. Long-term exposure of rabbits to imidaclorpid as quantified in blood induces genotoxic effect. Chemosphere. 2016 Feb 5;149:108-113.



29. Nitulescu GM, Margina D, Juzenas P, Peng Q, Olaru OT, Saloustros E, Fenga C, Spandidos DΑ, Libra M, Tsatsakis AM. Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review). Int J Oncol. 2016 Mar;48(3):869-85.

28. Ozcagli E, Alpertunga B, Fenga C, Berktas M, Tsitsimpikou C, Wilks MF, Tsatsakis ΑM. Effects of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites on DNA damage and repair under in vitro conditions. Food Chem Toxicol. 2015 Dec 31;89:1-7.

27. Ayse Basak Engin, Monica Neagu, Kirill Golokhvast, Aristidis Tsatsakis. Nanoparticles and endothelium: an update on the toxicological interactions.  FARMACIA, 2015, Vol. 63, 6

26. Spanidis Y., Goutzourelas N., Stagos D., Mpesios, A., Priftis A., Bar-Or, D., Spandidos D.A., Tsatsakis A.M., Leon, G., Kouretas, D. Variations in oxidative stress markers in elite basketball players at the beginning and end of a season. EXPERIMENTAL AND THERAPEUTIC MEDICINE. Volume 11, Issue 1, January 2016, Pages 147-153

25. Vardavas AI, Fragkiadaki P, Alegakis AK, Dimitrios K, Goutzourelas N, Tsiaoussis J, Tsitsimpikou C, Stivaktakis PD, Carvalho F, Tsatsakis AM. Downgrading the systemic condition of rabbits after long term exposure to cypermethrin and piperonyl butoxide. LIFE SCI. 2015 Dec 12. pii: S0024-3205(15)30119-3.

24. Vitkina TI, Yankova VI, Gvozdenko TA, Kuznetsov VL, Krasnikov DV, Nazarenko AV, Chaika VV, Smagin SV, Tsatsakis A, Engin AB, Karakitsios SP, Sarigiannis DA, Golokhvast KS. The impact of multi-walled carbon nanotubes with different amount of metallic impurities on immunometabolic parameters in healthy volunteers. FOOD CHEM TOXICOL. 2015 Dec 9. pii: S0278-6915(15)30109-5.

23. Georgakouli K, Manthou E, Fatouros IG, Deli CK, Spandidos DA, Tsatsakis AM, Kouretas D, Koutedakis Y, Theodorakis Y, Jamurtas AZ. Effects of acute exercise on liver function and blood redox status in heavy drinkers. EXP THER MED. 2015 Dec;10(6):2015-2022.

22. Margină D, Olaru OT, Ilie M, Grădinaru D, GuȚu C, Voicu S, Dinischiotu A, Spandidos DA, Tsatsakis AM. Assessment of the potential health benefits of certain total extracts from Vitis vinifera, Aesculus hyppocastanum and Curcuma longa. EXP THER MED. 2015 Nov;10(5):1681-1688.

21. Olaru OT, Venables L, VAN DE Venter M, Nitulescu GM, Margina D, Spandidos DA, Tsatsakis AM. Anticancer potential of selected Fallopia Adans species. ONCOL LETT. 2015 Sep;10(3):1323-1332.

20. Vasilaki F, Tsitsimpikou C, Tsarouhas K, Germanakis I, Tzardi M, Kavvalakis M, Ozcagli E, Kouretas D, Tsatsakis AM. Cardiotoxicity in rabbits after long-term nandrolone decanoate administration. TOXICOL LETT. 2015 Nov 2;241:143-151.

19. Piperigkou Z, Karamanou K, Afratis NA, Bouris P, Gialeli C, Belmiro CL, Pavão MS, Vynios DH, Tsatsakis AM. Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules. TOXICOL LETT. 2016 Jan 5;240(1):32-42.

18. García-García CR, Parrón T, Requena M, Alarcón R, Tsatsakis AM, Hernández AF. Occupational pesticide exposure and adverse health effects at the clinical, hematological and biochemical level. LIFE SCI. 2015 Oct 20. pii: S0024-3205(15)30039-4.

17. Priftis A, Stagos D, Konstantinopoulos K, Tsitsimpikou C, Spandidos DA, Tsatsakis AM, Tzatzarakis MN, Kouretas D. Comparison of antioxidant activity between green and roasted coffee beans using molecular methods. MOL MED REP. 2015 Nov;12(5):7293-302

16. Ozcagli E, Alpertunga B, Tsatsakis AM (2015) Biosimilar Drugs and Pharmacovigilance. Pharm Anal Acta 6: 416.

15. Carvalho F, Tsatsakis A. Preface. Toxicol Lett. 2015 Oct 16;238(2 Suppl):S1

14. Valente A, Carrillo AE, Tzatzarakis MN, Vakonaki E, Tsatsakis AM, Kenny GP, Koutedakis Y, Jamurtas AZ, Flouris AD. The absorption and metabolism of a single L-menthol ORAL versus SKIN administration: Effects on thermogenesis and metabolic rate. Food Chem Toxicol. 2015 Sep 28. [Epub ahead of print]

13. Moallem SA, Mohamadpour AH, Abnous K, Sankian M, Sadeghnia HR, Tsatsakis A, Shahsavand S. Erythropoietin in the treatment of carbon monoxide neurotoxicity in rat. Food Chem Toxicol. 2015 Sep 28;86:56-64. [Epub ahead of print]

12. Goutzourelas N, Stagos D, Spanidis Y, Liosi M, Apostolou A, Priftis A, Haroutounian S, Spandidos DA, Tsatsakis AM, Kouretas D. Polyphenolic composition of grape stem extracts affects antioxidant activity in endothelial and muscle cells. Mol Med Rep. 2015 Oct;12(4):5846-56. Epub 2015 Aug 12.

11. Golokhvast KS, Chernyshev VV, Chaika VV, Ugay SM, Zelinskaya EV, Tsatsakis AM, Karakitsios SP, Sarigiannis DA. Size-segregated emissions and metal content of vehicle-emitted particles as a function of mileage: Implications to population exposure. Environ Res. 2015 Aug 7;142:479-485. [Epub ahead of print]

10. Margină D, Ilie M, Grădinaru D, Androutsopoulos VP, Kouretas D, Tsatsakis AM. Natural products-friends or foes? Toxicol Lett. 2015 Aug 5;236(3):154-67. Epub 2015 May 14. Review.

9. Goutzourelas N, Stagos D, Housmekeridou A, Karapouliou C, Kerasioti E, Aligiannis N, Skaltsounis AL, Spandidos DA, Tsatsakis AM, Kouretas D. Grape pomace extract exerts antioxidant effects through an increase in GCS levels and GST activity in muscle and endothelial cells. Int J Mol Med. 2015 Aug;36(2):433-41. Epub 2015 Jun 15.

8. Golokhvast K, Vitkina T, Gvozdenko T, Kolosov V, Yankova V, Kondratieva E, Gorkavaya A, Nazarenko A, Chaika V, Romanova T, Karabtsov A, Perelman J, Kiku P, Tsatsakis A. Impact of Atmospheric Microparticles on the Development of Oxidative Stress in Healthy City/Industrial Seaport Residents. Oxid Med Cell Longev. 2015;2015:412173. Epub 2015 Apr 30.

7. Dragana Nikitovic, Maria Tzardi, Aikaterini Berdiaki, Aristidis Tsatsakis and George N. Tzanakakis Cancer microenvironment and inflammation: role of hyaluronan Front. Immunol., 14 April 2015 | [Epub ahead of print].

6. Kavvalakis MP, Stivaktakis PD, Tzatzarakis MN, Kouretas D, Liesivuori J, Alegakis AK, Vynias D, Tsatsakis AM. Multicomponent Analysis of Replacement Liquids of Electronic Cigarettes Using Chromatographic Techniques. J Anal Toxicol. 2015 Feb 13. pii: bkv002. [Epub ahead of print]. (IF: 2.627)

5. Tzatzarakis MN, Vakonaki E, Kovatsi L, Belivanis S, Mantsi M, Alegakis A, Liesivuori J, Tsatsakis AM. Determination of Buprenorphine, Norbuprenorphine and Naloxone in Fingernail Clippings and Urine of Patients Under Opioid Substitution Therapy. J Anal Toxicol. 2015 Feb 7. pii: bkv003. [Epub ahead of print]. (IF: 2.627)

4. Kerksick CM, Tsatsakis AM, Hayes AW, Kafantaris I, Kouretas D. How can bioinformatics and toxicogenomics assist the next generation of research on physical exercise and athletic performance.J Strength Cond Res. 2015 Jan;29(1):270-8. doi: 10.1519/JSC.0000000000000730.

3. Tsakiris IN, Goumenou M, Tzatzarakis MN, Alegakis AK, Tsitsimpikou C, Ozcagli E, Vynias D, Tsatsakis AM. Risk assessment for children exposed to DDT residues in various milk types from the Greek market.Food Chem Toxicol. 2015 Jan;75:156-65. doi: 10.1016/j.fct.2014.11.012. Epub 2014 Nov 20.

2. Manolis N. Tzatzarakis, Elena Vakonaki, Matthaios P. Kavvalakis, Michael Barmpas, Emmanouel N. Kokkinakis, Kyriakos Xenos, Aristidis M. Tsatsakis. Biomonitoring of bisphenol A in hair of Greek population.Chemosphere. 2015 Jan;118:336-41.

1. D.G. Sfakianakis, E.Renieri, M.Kentouri, A.M.Tsatsakis. Effect of heavy metals on fish larvae deformities. Environmental Research 137 (2015) 246–255.



13. Baltazar M.T., Dinis-Oliveira R.J., de Lourdes Bastos M., Tsatsakis A.M., Duarte J.A., Carvalho F. Pesticides exposure as etiological factors of Parkinson’s disease and other neurodegenerative diseases-A mechanistic approach, Toxicol. Lett. 230 (2014) 85–103.

12. Sahpazidou D., Geromichalos G.D., Stagos D., Apostolou A., Haroutounian S.A., Tsatsakis A.M., Tzanakakis G.N., Hayes A.W., Kouretas D. Anticarcinogenic activity of polyphenolic extracts from grape stems against breast , colon , renal and thyroid cancer cells, Toxicol. Lett. 230 (2014) 218–224.

11. Matsunaga Y, Vardavas CI, Plada M, Wärnberg J, Gómez-Martinez S, Tzatzarakis MN, Tsatsakis AM, Díaz EL, Marcos A, Kafatos AG.The relationship between cotinine concentrations and inflammatory markers among highly secondhand smoke exposed non-smoking adolescents. Cytokine. 2014 Mar;66(1):17-22.

10. Kerasioti E, Stagos D, Priftis A, Aivazidis S, Tsatsakis AM, Hayes AW, Kouretas D.Antioxidant effects of whey protein on muscle C2C12 cells. Food Chem. 2014 Jul 15;155:271-8.    

9. Koutroulakis D, Sifakis S, Tzatzarakis MN, Alegakis AK, Theodoropoulou E, Kavvalakis MP, Kappou D, Tsatsakis AM. Dialkyl phosphates in amniotic fluid as a biomarker of fetal exposure to organophosphates in Crete, Greece; association with fetal growth. Reprod Toxicol. 2014 Jul;46:98-105.  

8. Kavvalakis MP, Tzatzarakis MN, Alegakis AK, Vynias D, Tsakalof AK, Tsatsakis AM. Development and application of GC-MS method for monitoring of long-term exposure to the pesticide cypermethrin. Drug Test Anal. 2014 Jun;6

7. Tzatzarakis MN, Barbounis EG, Kavvalakis MP, Vakonaki E, Renieri E, Vardavas AI, Tsatsakis AM.Rapid method for the simultaneous determination of DDTs and PCBs in hair of children by headspace solid phase microextraction and gas chromatography-mass spectrometry (HSSPME/GC-MS). Drug Test Anal. 2014 Jun;6 Suppl 1:85-92.

6. Belivanis S, Tzatzarakis MN, Vakonaki E, Kovatsi L, Mantsi M, Alegakis A, Kavvalakis MP, Vynias D, Tsatsakis AM.Buprenorphine and nor-buprenorphine levels in head hair samples from former heroin users under Suboxone® treatment. Drug Test Anal. 2014 Jun;6 Suppl 1:93-100. 

5. Zafiropoulos A, Tsarouhas K, Tsitsimpikou C, Fragkiadaki P, Germanakis I, Tsardi M, Maravgakis G, Goutzourelas N, Vasilaki F, Kouretas D, Hayes A, Tsatsakis A. Cardiotoxicity in rabbits after a low-level exposure to diazinon, propoxur, and chlorpyrifos. Hum Exp Toxicol. 2014 May 12. [Epub ahead of print]

4. Spyrou I., Sifakis S., Ploumidis A., Papalampros A.E., Felekouras E., Tsatsakis A.M., Spandidos D.A., Androutsopoulos V.P. Expression profile of CYP1A1 and CYP1B1 enzymes in endometrial tumors, Tumor Biol. 35 (2014) 9549–9556.

3. Tsatsakis AM, Wallace H.Advancing science for human and environmental health - The 50th EUROTOX Congress.Toxicol Lett. 2014 Sep 10;229 Suppl:S1.  

2. Matthaiou CM, Goutzourelas N, Stagos D, Sarafoglou E, Jamurtas A, Koulocheri SD, Haroutounian SA, Tsatsakis AM, Kouretas D.Pomegranate juice consumption increases GSH levels and reduces lipid and protein oxidation in human blood.Food Chem Toxicol. 2014 Aug 1. pii: S0278-6915(14)00359-7 

1. Dinas PC, Metsios GS, Jamurtas AZ, Tzatzarakis MN, Wallace Hayes A, Koutedakis Y, Tsatsakis AM, Flouris AD. Acute effects of second-hand smoke on complete blood count. Int J Environ Health Res. 2014 Feb;24(1):56-62



29. Androutsopoulos VP, Tsatsakis AM. Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin-5-methyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism. Toxicol Lett. 2013 Aug 28. pii: S0378-4274(13)01277-0

 28. Juránek I, Nikitovic D, Kouretas D, Hayes AW, Tsatsakis AM. Biological importance of reactive oxygen species in relation to difficulties of treating pathologies involving oxidative stress by exogenous antioxidants. Food Chem Toxicol. 2013 Nov;61:240-7.

27. Kouretas D, Tsatsakis AM, Domingo JL, Wallace Hayes A. Mechanisms involved in oxidative stress regulation. Food Chem Toxicol. 2013 Nov;61:1-2. doi: 10.1016/j.fct.2013.10.016. Epub 2013 Oct 16.

 26. Tsakirakis AN, Kasiotis KM, Charistou AN, Arapaki N, Tsatsakis A, Tsakalof A, Machera K. Dermal & inhalation exposure of operators during fungicide application in vineyards. Evaluation of coverall performance. Sci Total Environ. 2013 Oct 17;470-471C:282-289.

25. Koureas M, Tsakalof A, Tzatzarakis M, Vakonaki E, Tsatsakis A, Hadjichristodoulou C. Biomonitoring of organophosphate exposure of pesticide sprayers and comparison of exposure levels with other population groups in Thessaly (Greece). Occup Environ Med. 2013 Nov 1. doi: 10.1136/oemed-2013-101490. [Epub ahead of print]

24. Tsakiris IN, Kokkinakis E, Dumanov JM, Tzatzarakis MN, Flouris AD, Vlachou M, Tsatsakis AM. Comparative evaluation of xenobiotics in human and dietary milk: persistent organic pollutants and mycotoxins. Cell Mol Biol (Noisy-le-grand). 2013 Nov 3;59(1):58-66.

23. Vinceti M, Mandrioli J, Borella P, Michalke B, Tsatsakis A, Finkelstein Y. Selenium neurotoxicity in humans: Bridging laboratory and epidemiologic studies. Toxicol Lett. 2013 Nov 22. pii: S0378-4274(13)01422-7.

22. Kavvalakis MP, Tzatzarakis MN, Theodoropoulou EP, Barbounis EG, Tsakalof AK, Tsatsakis AM. Development and application of LC–APCI–MS method for biomonitoring of animal and human exposure to imidacloprid. Chemosphere. 2013 Nov;93(10):2612-20.

21.Androutsopoulos VP, Spyrou I, Ploumidis A, Papalampros AE, Kyriakakis M, Delakas D, Spandidos DA, Tsatsakis AM. Expression Profile of CYP1A1 and CYP1B1 Enzymes in Colon and Bladder Tumors. PLoS One. 2013 Dec 16;8(12)

20. Michalakis M, Tzatzarakis MN, Kovatsi L, Alegakis AK, Tsakalof AK, Heretis I, Tsatsakis A. Hypospadias in offspring is associated with chronic exposure of parents to organophosphate and organochlorine pesticides.Toxicol Lett. 15 October 2014, Pages 139–145.

19. Gubandru M, Margina D, Tsitsimpikou C, Goutzourelas N, Tsarouhas K, Ilie M, Tsatsakis AM, Kouretas D. Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers. Food Chem Toxicol. 2013 Nov;61:209-14.

18. Flouris AD, Dinas PC, Tzatzarakis MN, Metsios GS, Kostikas K, Jamurtas AZ, Tsatsakis AM, Koutedakis Y. Exposure to secondhand smoke promotes sympathetic activity and cardiac muscle cachexia. Int J Environ Health Res. 2013 Jun 26. [Epub ahead of print]

17. Nikitovic D, Corsini E, Kouretas D, Tsatsakis A, Tzanakakis G. ROS-major mediators of extracellular matrix remodeling during tumor progression. Food Chem Toxicol. 2013 Nov;61:178-86.

16. Hernández AF, Gil F, Lacasaña M, Rodríguez-Barranco M, Tsatsakis AM, Requena M, Parrón T, Alarcón R. Pesticide exposure and genetic variation in xenobiotic-metabolizing enzymes interact to induce biochemical liver damage. Food Chem Toxicol. 2013 Nov;61:144-51.

15.Colosio C, Alegakis AK, Tsatsakis AM.Emerging health issues from chronic pesticide exposure: innovative methodologies and effects on molecular cell and tissue level. Toxicology. 2013 May 10;307:1-2.

14. Kerksick CM, Willoughby D, Kouretas D, Tsatsakis A. Intramuscular responses with muscle damaging exercise and the interplay between multiple intracellular networks: A human perspective. Food Chem Toxicol. 2013 Nov;61:136-43.

13. Prodanchuk MG, Tsatsakis AM, Prodanchuk GM, Tsakalof AK. Investigation of in vivo toxicity of hydroxylamine sulfate and the efficiency of intoxication treatment by α-tocopherol acetate and methylene blue. Food Chem Toxicol. 2013 Nov;61:227-32.

12. Mrema EJ, Rubino FM, Brambilla G, Moretto A, Tsatsakis AM, Colosio C. Persistent organochlorinated pesticides and mechanisms of their toxicity. Toxicology. 2013 May 10;307:74-88.

11. Nikitovic D, Berdiaki A, Banos A, Tsatsakis A, Karamanos NK, Tzanakakis GN.bCould growth factor-mediated extracellular matrix deposition and degradation offer the ground for directed pharmacological targeting in fibrosarcoma? Curr Med Chem. 2013;20(23):2868-80.

10. Flouris A.D., Chorti M.S., Poulianiti K.P., Jamurtas A.Z., Kostikas K., Tzatzarakis M.N., Wallace Hayes A., Tsatsakis A.M., Koutedakis Y. Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function, Inhal. Toxicol. 25 (2013) 91–101.

9. Germanakis I, Tsarouhas K, Fragkiadaki P, Tsitsimpikou C, Goutzourelas N, Champsas MC, Stagos D, Rentoukas E, Tsatsakis AM. Oxidative stress and myocardial dysfunction in young rabbits after short term anabolic steroids administration. Food Chem Toxicol. 2013 Nov;61:101-5.

8. Corsini E, Galbiati V, Nikitovic D, Tsatsakis AM. Role of oxidative stress in chemical allergens induced skin cells activation. Food Chem Toxicol. 2013 Nov;61:74-81. doi

7. Tsakiris IN, Tzatzarakis MN, Alegakis AK, Vlachou MI, Renieri EA, Tsatsakis AM. Risk assessment scenarios of children's exposure to aflatoxin M1 residues in different milk types from the Greek market. Food Chem Toxicol. 2013 Jun;56:261-5.

6.Zaganas I, Kapetanaki S, Mastorodemos V, Kanavouras K, Colosio C, Wilks MF, Tsatsakis AM. Linking pesticide exposure and dementia: what is the evidence? Toxicology. 2013 May 10;307:3-11.

5.Apostolou A, Stagos D, Galitsiou E, Spyrou A, Haroutounian S, Portesis N, Trizoglou I, Wallace Hayes A, Tsatsakis AM, Kouretas D. Assessment of polyphenolic content, antioxidant activity, protection against ROS-induced DNA damage and anticancer activity of Vitis vinifera stem extracts. Food Chem Toxicol. 2013 Nov;61:60-8.

4. Kerasioti E, Stagos D, Jamurtas A, Kiskini A, Koutedakis Y, Goutzourelas N, Pournaras S, Tsatsakis AM, Kouretas D. Anti-inflammatory effects of a special carbohydrate-whey protein cake after exhaustive cycling in humans. Food Chem Toxicol. 2013 Nov;61:42-6.

3. Vakonaki E, Androutsopoulos VP, Liesivuori J, Tsatsakis AM, Spandidos DA. Pesticides and oncogenic modulation. Toxicology. 2013 May 10;307:42-5.

2. Dardiotis E, Xiromerisiou G, Hadjichristodoulou C, Tsatsakis AM, Wilks MF, Hadjigeorgiou GM. The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides. Toxicology. 2013 May 10;307:17-23.

1. Kovatsi L, Batzios S, Nikolaou K, Fragou D, Njau S, Tsatsakis A, Karakiulakis G, Papakonstantinou E. Alterations in serum MMP and TIMP concentrations following chronic heroin abuse. Toxicol Mech Methods. 2013 Jun;23(5):377-81.



25. Kovatsi L, Batzios S, Nikolaou K, Fragou D, Njau S, Tsatsakis A, Karakiulakis G, Papakonstantinou E. Alterations in serum MMP and TIMP concentrations following chronic heroin abuse.Toxicology Mechanisms and Methods.

24. MP Kavvalakis, AM Tsatsakis. The atlas of dialkylphosphates; assessment of cumulative human organophosphorus pesticides’ exposure. Forensic science international.

23. M Koureas, A Tsakalof, A Tsatsakis, C Hadjichristodoulou. Systematic review of biomonitoring studies to determine the association between exposure to organophosphorus and pyrethroid insecticides and human health outcomes. Toxicology letters.

22. Stagos D, Amoutzias GD, Matakos A, Spyrou A, Tsatsakis AM, Kouretas D. Chemoprevention of liver cancer by plant polyphenols. Food Chem Toxicol.

21. BMR Appenzeller, AM Tsatsakis. Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: State of the art, critical review and future needs. Toxicology letters.

20. Tsitsimpikou C, Tzatzarakis M, Fragkiadaki P, Kovatsi L, Stivaktakis P, Kalogeraki A, Kouretas D, Tsatsakis AM. Histopathological lesions, oxidative stress and genotoxic effects in liver and kidneys following long term exposure of rabbits to diazinon and propoxur. Toxicology.

19. Mrema EJ, Rubino FM, Brambilla G, Moretto A, Tsatsakis AM, Colosio C. Persistent organochlorinated pesticides and mechanisms of their toxicity. Toxicology.

18. VP Androutsopoulos, AF Hernandez, J Liesivuori, AM Tsatsakis. A mechanistic overview of health associated effects of low levels of organochlorine and organophosphorous pesticides. Toxicology   

17. D Nikitovic, G Chatzinikolaou, J Tsiaoussis, A Tsatsakis, NK Karamanos. Insights into Targeting Colon Cancer Cell Fate at the Level of Proteoglycans/Glycosaminoglycans. Current Medicinal Chemistry 19 (25), 4247-4258.

16. Z Vlata, A Tsatsakis, M Tzagournissakis, E Krambovitis Endocrine. Evaluation of Specific Immune Responses to BoNT/A and Tetanus Toxoid in Patients Undergoing Treatment for Neurologic Disorders. Metabolic & Immune Disorders-Drug Targets (Formerly Current Dru 12 (3) 268-273

15. C Papandreou, SE Schiza, MN Tzatzarakis, M Kavalakis, CM Hatzis, Aristidis M Tsatsakis. Effect of Mediterranean diet on lipid peroxidation marker TBARS in obese patients with OSAHS under CPAP treatment: a randomised trial. Sleep and Breathing 16 (3), 873-879.

14. D Stagos, N Portesis, C Spanou, Aristidis M Tsatsakis, D Mossialos, N Aligiannis, E Chaita.Correlation of total polyphenolic content with antioxidant and antibacterial activity of 24 extracts from Greek domestic Lamiaceae species. Food and Chemical Toxicology.

13. AD Flouris, KP Poulianiti, MS Chorti, AZ Jamurtas, D Kouretas, EO Owolabi, Aristidis M Tsatsakis. Acute Effects of Electronic and Tobacco Cigarette Smoking on Complete Blood Count. Food and Chemical Toxicology.

12. S Surichan, VP Androutsopoulos, S Sifakis, E Koutala, AM Tsatsakis. Bioactivation of the citrus flavonoid nobiletin by CYP1 enzymes in MCF7 breast adenocarcinoma cells. S Food and Chemical Toxicology.

11. AF Hernández, T Parrón, AM Tsatsakis, M Requena, R Alarcón, O López-Guarnido. Toxic effects of pesticide mixtures at a molecular level: their relevance to human health. Toxicology.

10. EG Barbounis, MN Tzatzarakis, AK Alegakis, A Kokkinaki, N Karamanos, Aristidis M Tsatsakis.Assessment of PCBs exposure in human hair using double focusing high resolution mass spectrometry and single quadrupole mass spectrometry. Toxicology letters 210 (2), 225-231.

9. AM Tsatsakis, M Christakis-Hampsas, J Liesivuori. The increasing significance of biomonitoring for pesticides and organic pollutants. Toxicology letters 210 (2), 107.

8. E Kerasioti, A Kiskini, A Veskoukis, A Jamurtas, C Tsitsimpikou, Aristidis M Tsatsakis. Effect of a special carbohydrate-protein cake on oxidative stress markers after exhaustive cycling in humans. Food and Chemical Toxicology.

7. MN Tzatzarakis, CI Vardavas, I Terzi, M Kavalakis, M Kokkinakis, Aristidis M Tsatsakis. Hair nicotine/cotinine concentrations as a method of monitoring exposure to tobacco smoke among infants and adults. Human & experimental toxicology 31 (3), 258-265.

6. Tsatsakis AM, Tutudaki M, Tzatzarakis MN, Dawson A, Mohamed F, Christaki M, Alegakis AK. Is hair analysis for dialkyl phosphate metabolites a suitable biomarker for assessing past acute exposure to organophosphate pesticides? Hum Exp Toxicol. 2012 Mar;31(3):266-73.

5. BMR Appenzeller, AM Tsatsakis. Reply to: A commentary on “Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants. Toxicology letters.

4. AD Flouris, GS Metsios, AE Carrill, AZ Jamurtas, PD Stivaktakis, Aristidis M Tsatsakis. Respiratory and Immune Response to Maximal Physical Exertion following Exposure to Secondhand Smoke in Healthy Adults.PloS one 7 (2), e31880.

3. FM Rubino, S Mandic-Rajcevic, E Ariano, A Alegakis, M Bogni, G Brambilla, Aristidis M Tsatsakis. Farmers’ exposure to herbicides in North Italy: Assessment under real-life conditions in small-size rice and corn farms. Toxicology letters.

2. VF Diakonis, MA Grentzelos, MN Tzatzarakis, V Kankaria, A Karavitaki, Aristidis M Tsatsakis.Riboflavin's time-dependent degradation rate induced by ultraviolet A irradiation. European Journal of Ophthalmology 22 (3), 51.

1. AS Veskoukis, AM Tsatsakis, D Kouretas. Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration. Cell Stress and Chaperones 17 (1), 11-21.



12. G Chalkiadaki, D Nikitovic, P Katonis, A Berdiaki, AM Tsatsakis. Low molecular weight heparin inhibits melanoma cell adhesion and migration through a PKCa/JNK signaling pathway inducing actin cytoskeleton changes. Cancer Letters 312 (2), 235-244.

11. AN Loukopoulou, CI Vardavas, G Farmakides, C Rossolymos, C Chrelias, Tsatsakis AM. Design and study protocol of the maternal smoking cessation during pregnancy study,(M-SCOPE). BMC public health 11 (1), 903.

10. Kanavouras K, Tzatzarakis MN, Mastorodemos V, Plaitakis A, Tsatsakis AM. A case report of motor neuron disease in a patient showing significant level of DDTs, HCHs and organophosphate metabolites in hair as well as levels of hexane and toluene in blood. Toxicol Appl Pharmacol. 2011 Nov 1;256(3):399-404.

9. Androutsopoulos VP, Kanavouras K, Tsatsakis AM. Role of paraoxonase 1 (PON1) in organophosphate metabolism: implications in neurodegenerative diseases. Toxicol Appl Pharmacol. 2011 Nov 1;256(3):418-24.

8. G Maravgakis, MN Tzatzarakis, AK Alegakis, PD Stivaktakis, AM Tsatsakis. Diethyl phosphates accumulation in rabbits’ hair as an indicator of long term exposure to diazinon and chlorpyrifos. Forensic science international.

7. Tsatsakis AM, Androutsopoulos VP, Zafiropoulos A, Babatsikou F, Alegakis T, Dialyna I, Tzatzarakis M, Koutis C. Associations of xenobiotic-metabolizing enzyme genotypes PON1Q192R, PON1L55M and CYP1A1*2A MspI with pathological symptoms of a rural population in south Greece. Xenobiotica. 2011 Oct;41(10):914-25.

6. AM Tsatsakis, A Alegakis, E Ariano, G Brambilla, S Mandic-Rajcevic. Integration of biological monitoring, environmental monitoring and computational modelling into the interpretation of pesticide exposure data: Introduction to a proposed approach. C Colosio, FM Rubino. Toxicology Letters.

5. AA Artyukhov, MI Shtilman, AN Kuskov, AP Fomina, DE Lisovyy, AS Golunova, AM Tsatsakis.Macroporous polymeric hydrogels formed from acrylate modified polyvinyl alcohol macromers.
Journal of Polymer Research 18 (4), 667-673.

4. Tsakirakis A, Kasiotis KM, Arapaki N, Charistou A, Tsatsakis A, Glass CR, Machera K. Determination of operator exposure levels to insecticide during bait applications in olive trees: Study of coverall performance and duration of application. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH 2010, 13 Sept, In press.

3. Artyukhov AA, Shtilman MI, Kuskov AN, Pashkova LI, Tsatsakis AM, Rizos AK. Polyvinil alcohol cross-linked macroporous polymeric hydrogels: Structure formation and regularity investigation. JOURNAL OF NON-CRYSTALLINE SOLIDS 2010, 7 Sept, In press.

2. Tsitsimpikou C, Chrisostomou N, Papalexis P, Tsarouhas K, Tsatsakis A, Jamurtas A. The use of nutritional supplements among recreational athletes in Athens, Greece. Int J Sport Nutr Exerc Metab. 2011 Oct;21(5):377-84.

ИА Григорюк, НШ Ормоцадзе, AM Tsatsakis, GG Allan



15. Tsarouhas K., Soufla G., Apostolakis S., Zaravinos A., Panagiotou M., Khoury M., Hassoulas J.A., Tsatsakis A.M., Spandidos D.A. Transcriptional regulation of TIMPs in ascending aorta aneurysms, Thromb. Res. 126 (2010) 399–405.

14. Artyukhov A.A., Shtilman M.I., Kuskov A.N., Fomina A.P., Lisovyy D.E., Golunova A.S., Tsatsakis A.M. Macroporous polymeric hydrogels formed from acrylate modified polyvinyl alcohol macromers, J. Polym. Res. 18 (2011) 667–673.

13.Vardavas C.I., Plada M., Tzatzarakis M., Marcos A., Warnberg J., Gomez-Martinez S., Breidenassel C., Gonzalez-Gross M., Tsatsakis A.M., Saris W.H., Moreno L.A., Kafatos A.G. Passive smoking alters circulating naïve/memory lymphocyte T-cell subpopulations in children, Pediatr. Allergy Immunol. 21 (2010) 1171–1178.

12. Papadantonakis P., Neofotistou O., Vasiliadi A., Skoutelis A., Tsatsakis A., Tosca A., Krüger-Krasagakis S. Porphyria cutanea tarda and beta-thalassaemia major: Causal or casual?, J. Eur. Acad. Dermatology Venereol. 24 (2010) 1242–1243.

11. Tsatsakis A.M., Barbounis M.G., Kavalakis M., Kokkinakis M., Terzi I., Tzatzarakis M.N. Determination of dialkyl phosphates in human hair for the biomonitoring of Exposure to organophosphate pesticides, J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 878 (2010) 1246–1252.

10. Vardavas C.I., Tzatzarakis M.N., Plada M., Tsatsakis A M., Papadaki A, Saris W.H., Moreno L. A, Kafatos A G. Biomarker evaluation of Greek adolescents’ exposure to secondhand smoke., Hum. Exp. Toxicol. 29 (2010) 459–66.

9. Symvoulakis EK, Vardavas CI, Fountouli P, Stavroulaki A, Antoniou KM, Duijker G, Tzatzarakis MN, Sfiridaki K, Bolonaki E, Alegakis T, Tsatsakis AM. Time interval from cigarette smoke exposure to blood donation and markers of inflammation: should a smoking cut-off be designated? XENOBIOTICA 2010, 40(9):613-620.

8. Kuskov AN, Voskresenskaya AA, Goryachaya AV, Shtilman MI, Spandidos DA, Rizos AK, Tsatsakis AM. Amphiphilic poly-N-vinylpyrrolidone nanoparticles as carriers for non-steroidal anti-inflammatory drugs: characterization and in vitro controlled release of indomethacin. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2010, 26(1):85-94.

7. Zafiropoulos A, Linardakis M, Jansen EH, Tsatsakis AM, Kafatos A, Tzanakakis GN. Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue. JOURNAL OF LIPID RESEARCH 2010, 51(7):1991-2000.

6. Kuskov AN, Voskresenskaya AA, Goryachaya AV, Artyukhov AA, Shtilman MI, Tsatsakis AM. Preparation and characterization of amphiphilic poly-N-vinylpyrrolidone nanoparticles containing indomethacin. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 2010, 21(5):1521-1530.

5. Berdiaki A, Datsis GA, Nikitovic D, Tsatsakis A, Katonis P, Karamanos NK, Tzanakakis GN. Parathyroid hormone (PTH) peptides through the regulation of hyaluronan metabolism affect osteosarcoma cell migration. IUBMB LIFE 2010, 62(5):377-386.

4. Androutsopoulos VP, Papakyriakou A, Vourloumis D, Tsatsakis AM, Spandidos DA. Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes. Review. PHARMACOLOGY & THERAPEUTICS 2010, 126(1):9-20.

3. Claude N, Christakis M, Tsatsakis AM. Stem cells technologies in toxicology assessments. TOXICOLOGY 2010, 30;270(1):1-2.

2. Saroglou M, Tryfon S, Ismailos G, Liapakis I, Tzatzarakis M, Tsatsakis A, Papalois A, Bouros D. Pharmacokinetics of Linezolid and Ertapenem in experimental parapneumonic pleural effusion. JOURNAL OF INFLAMMATION-LONDON 2010, 18;7:22.

1. Flouris AD, Vardavas CI, Metsios GS, Tsatsakis AM, Koutedakis Y. Biological evidence for the acute health effects of secondhand smoke exposure. Review. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 2010, 298(1):L3-L12.



13. Tsatsakis A M., Tzatzarakis M.N., Koutroulakis D., Toutoudaki M., Sifakis S. Dialkyl phosphates in meconium as a biomarker of prenatal exposure to organophosphate pesticides: a study on pregnant women of rural areas in Crete, Greece., Xenobiotica. 39 (2009) 364–73.

12. Krasagakis K., Kruger-Krasagakis S., Eberle J., Tsatsakis A., Tosca A.D., Stathopoulos E.N. Co-expression of KIT receptor and its ligand stem cell factor in Merkel cell carcinoma., Dermatology. 218 (2009) 37–43

11. Margariti M., Tsatsakis A.M. Assessment of long-term subacute exposure to dimethoate by hair analysis of dialkyl phosphates DMP and DMTP in exposed rabbits: the effects of dose, dose duration and hair colour.ENVIRONMENTAL RESEARCH 2009, 109(7):821-829.

10. Androutsopoulos VP, Ruparelia K, Arroo RR, Tsatsakis AM, Spandidos DA.CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells. TOXICOLOGY 2009, 29;264(3):162-170.

9. Disputed case of homicide by smothering due to severe amitriptyline intoxication of the victim.
I Stiakakis, SD Belivanis, MN Tzatzarakis, M Fragoulis, AM Tsatsakis
Journal of forensic and legal medicine 16 (5), 280-283.

8. Androutsopoulos VP, Tsatsakis AM, Spandidos DA. Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention. Review BMC CANCER 2009, 16;9:187.

7. Flouris AD, Metsios GS, Carrillo AE, Jamurtas AZ, Germenis AE, Gourgoulianis K, Kiropoulos T, Tzatzarakis MN, Tsatsakis AM, Koutedakis Y. Acute and short-term effects of secondhand smoke on lung function and cytokine production. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2009, 1;179(11):1029-1033.

6. Margariti, M.G., Tsatsakis, A.M. Analysis of dialkyl phosphate metabolites in hair using gas chromatography-mass spectrometry: a biomarker of chronic exposure to organophosphate pesticides. BIOMARKERS 2009, 14(3), 137-147.

5. Tsatsakis A.M., Tzatzarakis, M.N., Koutroulakis, D., Toutoudaki, M., Sifakis, S. Dialkyl phosphates in meconium as a biomarker of prenatal exposure to organophosphate pesticides: A study on pregnant women of rural areas in Crete, Greece. XENOBIOTICA 2009, 39(5):364-373.

4. Tsatsakis A.M.Pesticide exposure levels in general and rural population ENVIRONMENTAL RESEARCH 2009, 109(3), 350-351.

3. RI Tashmukhamedov, MV Klyagina, VY Khvostova, AV Goryachaya, MI Shtil'man, AM Tsatsakis. PM 07/11/21-Transl. serial no. 15947-Complexes of transition metals based on amino acid derivatives of epoxy-containing poly-N-vinylpyrrolidone. International Polymer Science and Technology 36 (1), 17.

2. AM Tsatsakis, M Toutoudaki, M Tzatzarakis. Assessing Chronic Exposure to Anticholinesterase Pesticides by Hair Analysis. Counteraction to Chemical and Biological Terrorism in East European Countries 203-211.

1. Kymionis GD, Diakonis VF, Panagopoulou SI, Grentzelos MA, Kazakos DC, Tzatzarakis MN, Tsatsakis AM, Pallikaris AI. Mitomycin C aqueous humor concentration after photorefractive keratectomy: an experimental study. EUROPEAN JOURNAL OF OPHTHALMOLOGY 2009,19(5):738-742.



9. Tsatsakis AM, Zafiropoulos A, Tzatzarakis MN, Tzanakakis GN, Kafatos A.. Relation of PON1 and CYP1A1 genetic polymorphisms to clinical data in a cross-sectional study of a Greek population professionally exposed to pesticides. TOXICOLOGY LETTERS 2009, 186(1), 66-72 Epub Oct 28 2008.

8. Tsatsakis A.M., Tzatzarakis M.N, Tutudaki M., Babatsikou F., Alegakis A.K., Koutis Ch. Assessment of levels of organochlorine pesticides and their metabolites in the hair of a Greek rural human population. HUMAN & EXPERIMENTAL TOXICOLOGY 2008, 27(12), 933-940.

7. Nikitovic D, Katonis P, Tsatsakis A, Karamanos NK, Tzanakakis GN. Lumican, a small leucine-rich proteoglycan. IUBMB LIFE 2008 ;60(12):818-823.

6. Zafiropoulos A., Nikitovich D., Katonis P., Tsatsakis AM, Karamanos NK and Tzanakakis GN. Decorin-induced growth inhibition is overcomethrough protracted expression and activation of EGFRs in osteosarcoma cells. MOLECULAR CANCER RESEARCH 2008, 6(5), 785-794.

5. Chatzinikolaou G., Nikitovic, D., Asimakopoulou A., Tsatsakis A.,  Karamanos N., Tzanakakis G.N. Heparin - a unique stimulator of human colon cancer cells growth. IUBMB LIFE 2008, 60(5), 333-340.

4. Fthenou E, Zafiropoulos A, Katonis P, Tsatsakis A, Karamanos NK, Tzanakakis GN. Chondroitin sulfate prevents platelet derived growth factor-mediated phosphorylation of PDGF-Rbeta in normal human fibroblasts severely impairing mitogenic responses. JOURNAL OF CELLULAR BIOCHEMISTRY 2008, 103(6), 1866-1876.

3.Tsatsakis AM, Tzatzarakis MN, Tutudaki M. Pesticide levels in head hair samples of Cretan population as an indicator of present and past exposure. FORENSIC SCIENCE INTERNATIONAL 2008, 176(1), 67-71.

2. Berdiaki A., Zafiropoulos A., Fthenou E., Katonis P., Tsatsakis AM, Karamanos NK and Tzanakakis GN. Regulation of hyaluronan and versican deposition by growth factors in fibrosarcoma cell lines. BIOCHIMICA ET BIOPHYSICA ACTA (BBA). General Subjects, 2008 1780(2), 194-202.

1. Nikitovic D, Berdiaki A, Zafiropoulos A, Katonis P, Tsatsakis A, Karamanos NK, Tzanakakis GN. Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells.  FEBS JOURNAL 2008, 275(2):350-361. Epub 2007 Dec 17.



6. Kuskov, A.N., Shtilman, M.I., Goryachaya, A.V., Tashmuhamedov, R.I., Yaroslavov, A.A., Torchilin, V.P., Tsatsakis, A.M., Rizos, A.K. Self-assembling nanoscaled drug delivery systems composed of amphiphilic poly-N-vinylpyrrolidones. JOURNAL OF NON-CRYSTALLINE SOLIDS. 2007, 353 (41-43), 3969-3975.

5. Kuskov, A.N., Villemson, A.L., Shtilman, M.I., Larionova, N.I., Tsatsakis, A.M., Tsikalas, I., Rizos, A.K.  Amphiphilic poly-N-vinylpyrrolidone nanocarriers with incorporated model proteins. JOURNAL OF PHYSICS-CONDENSED MATTER 2007, 19 (20), art. no. 205139. 11p.

4. Margariti, M.G., Tsakalof, A.K., Tsatsakis, A.M.  Analytical methods of biological monitoring for exposure to pesticides: Recent update. THERAPEUTIC DRUG MONITORING. 2007, 29 (2), . 150-163.

3. A Rizos, I Tsikalas, A Tsatsakis, M Shtilman. Erratum to Characterization of amphiphilic poly-N-vinylpyrrolidone derivatives by dynamic light scattering. Journal of Non Crystalline Solids 353, 221-221.

2. ТРИ Rizos АК, AM Tsatsakis, МВ Клягина, АВ Горячая, МИ Штильман. Агрегация в водном растворе аминокислотных производных поли-N-винилпирролидона. Пластические массы, 19-20.

1. РИ Ташмухамедов, МВ Клягина, ГАВ Xвocтoвa ВЮ, МИ Штильман, AM Tsatsakis. Комплексы переходных металлов на основе аминокислотных производных эпоксид-содержащего поли-n-винилпирролидона. Пластические массы, 21-22.



8. Fthenou E, Zafiropoulos A, Tsatsakis A, Stathopoulos A, Karamanos NK, Tzanakakis GN. Chondroitin sulfate A chains enhance platelet derived growth factor-mediated signalling in fibrosarcoma cells. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 2006;38(12):2141-2150.

7. Rizos, A.K., Tsikalas, I., Tsatsakis, A.M., Shtilman, M.I.  Characterization of amphiphilic poly-N-vinylpyrrolidone derivatives by dynamic light scattering'. JOURNAL OF NON-CRYSTALLINE SOLIDS. 2006, 352, 5055-5059.

6. Vlata Z, Porichis F, Tzanakakis G, Tsatsakis A, Krambovitis E. A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells. TOXICOLOGY LETTERS 2006 Sep 10;165(3):274-281.

5. Shtilman MI, Tzatzarakis MN, Voskanyan PS, Tsakiris IN, Tsakalof, A.K., Tsatsakis, A.M. Correlation between plant growth regulator release rate and bioactivity for the series of newly synthesized phytoactive polymers. JOURNAL OF PLANT GROWTH REGULATION 2006, 25 (3), 211-218.

4. Charvalos E, Tzatzarakis MN, Van Bambeke F, Tulkens PM, Tsatsakis AM, Tzanakakis GN, Mingeot-Leclercq MP. Water-soluble amphotericin B-polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects.  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2006 Feb;57(2):236-244. Epub 2005 Dec 16.

3. Модификация латексных систем полимерными комплексами сорбиновой 33 кислоты. АГ Снежко, АВ Федотова, ЗС Борисова, ЮА Филинская, МИ Штильман, ОВ Супрун Пластические массы, 33-36.

2. Shtilman MI, Artyukhov AA, Zolotaikina TS, Korshak AY, Gorchakov AV, Tsatsakis AM. Crosslinked macroporous polymeric hydrogels of polyvinyl alcohol: a study of the influence of the synthesis conditions. International Polymer Science and Technology 33 (10), 25-30

1. D Nikitovic, A Zafiropoulos, P Katonis, AM Tsatsakis, AD Theocharis. Transforming Growth Factor‐β as a key molecule triggering the expression of versican isoforms v0 and v1, Hyaluronan Synthase‐2 and synthesis of Hyaluronan in Malignant Osteosarcoma cells. IUBMB life 58 (1), 47-53



7. Vlata Z, Porichis F, Tzanakakis G, Tsatsakis A, Krambovitis E. In vitro cytopathic effects of mycotoxin T-2 on human peripheral blood T lymphocytes. TOXICOLOGY LETTERS 2005, 30;160(1):60-68. Epub 2005 Jul 14.

6. Tutudaki M, Tsatsakis AM. Pesticide hair analysis: development of a GC-NCI-MS method to assess chronic exposure to diazinon in rats. JOURNAL OF ANALYTICAL TOXICOLOGY 2005, 29(8):805-809.

5. S Sifakis, E Angelakis, A Makrigiannakis, I Orfanoudaki, M Christakis, AM Tsatsakis. Chemoprophylactic and bactericidal efficacy of 80 mg gentamicin in a single and once-daily dosing. Archives of gynecology and obstetrics 272 (3), 201-206.

4. Nikitovic D, Zafiropoulos A, Tzanakakis GN, Karamanos NK, Tsatsakis AM.  Effects of glycosaminoglycans on cell proliferation of normal osteoblasts and human osteosarcoma cells depend on their type and fine chemical compositions. ANTICANCER RESEARCH 2005, 25(4):2851-2856.

3. Savvopoulos MA, Pallis E, Tzatzarakis MN, Dialyna IA, Tzanakakis G, Tsatsakis AM. Legal issues of addiction assessment. The experience with hair testing in Greece. JOURNAL OF APPLIED TOXICOLOGY 2005, 25(2), 143-152.

2. RI Tashmukhamedov, MI Shtil'man, VY Khvostova, MV Klyagina, AM Tsatsakis. Poly (N-vinylpyrrolidone) with amino acid side groups. Polymer science. Series B 47 (5-6), 167-169

1. Papanikolaou NC, Hatzidaki EG, Belivanis S, Tzanakakis GN, Tsatsakis AM. Lead toxicity update. A brief review. MEDICAL SCIENCE MONITOR 2005 Oct;11(10):RA329-336. Epub 2005 Sep 26.



7. Bertsias GK, Katonis P, Tzanakakis G, Tsatsakis AM. Review of clinical and toxicological features of acute pesticide poisonings in Crete (Greece) during the period 1991-2001. MEDICAL SCIENCE MONITOR  2004, 10(11):CR622-627.

6. Tsatsakis AM, Tutudaki M. Progress in pesticide and POPs hair analysis for the assessment of exposure. FORENSIC SCIENCE INTERNATIONAL 2004, 29;145(2-3):195-199.

5. Liapakis IE, Kottakis I, Tzatzarakis MN, Tsatsakis AM, Pitiakoudis MS, Ypsilantis P, Light RW, Simopoulos CE, Bouros DE. Penetration of newer quinolones in the empyema fluid. EUROPEAN RESPIRATORY JOURNAL 2004, 24(3):466-470.

4. Mantzouranis EC, Bertsias GK, Pallis EG, Tsatsakis AM. Hair analysis differentiates chronic from acute carbamazepine intoxication. PEDIATRIC NEUROLOGY 2004, 31 (1): 73-75.

3. Tsakiris IN, Danis TG, Stratis IA, Alegakis T, Dialyna I, Tsatsakis AM. Monitoring of pesticide residues in fresh peaches produced under conventional and integrated crop management cultivation. FOOD ADDITIVES AND CONTAMINANTS 2004, 21 (7): 670-677.

2. Dialyna I., Tzanakakis G, Dolapsakis G, Tsatsakis AM. A tetranucleotide repeat polymorphism in the CYP19 gene and breast cancer susceptibility in a Greek population exposed and not exposed to pesticides. TOXICOLOGY LETTERS  2004, 151 (1): 267-271.

1. МИ Штильман, ОВ Супрун, E Tzatzarakis, ММ Лоттер, Tsatsakis AM, ТЛ Лебедева, АВ Харенко. Комплексы поли-N-винилпирролидона и сорбиновой кислоты. Пластические массы, 23-27.



6. Tzanakakis GN, Margioris AN, Tsatsakis AM, Vezeridis MP. The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity. INTERNATIONAL JOURNAL OF GASTROINTESTINAL CANCER 2003, 34(1):27-38.

5. Tsatsakis AM, Tsakiris IN, Tzatzarakis MN, Agourakis ZB, Tutudaki M, Alegakis A. Three-year study of fenthion and dimethoate pesticides in olive oil from organic and conventional cultivation. FOOD ADDITIVES AND CONTAMINANTS 2003, 20 (6): 553-559.

4. Tutudaki M, Tsakalof AK, Tsatsakis AM. Hair analysis used to assess chronic exposure to the organophosphate diazinon: a model study with rabbits. HUMAN & EXPERIMENTAL TOXICOLOGY 2003, 22 (3): 159-164.

3. MI Shtil man, GY Ostaeva, AA Artyukhov, AM Tsatsakis, VS Kozlov. PM 02/03/25 Transl. serial no. 14827 Epoxy-containing porous hydrogels of acrylamide: The influence of the synthesis conditions.
International Polymer Science and Technology 30 (1), 47-52

2. MI Shtil man, AA Artyukhov, VS Kozlov, AM Tsatsakis. Epoxy-containing porous hydrogels of poly (2-hydroxyethyl methacrylate): A study of the influence of the synthesis conditions.
International Polymer Science and Technology 30 (4), 73-78

1. Nikitovic D, Tsatsakis AM, Karamanos NK, Tzanakakis G. The effects of genistein on the synthesis and distribution of glycosaminoglycans/ proteoglycans by two osteosarcoma cell lines depends on tyrosine kinase and the estrogen receptor density. ANTICANCER RESEARCH 2003, 23 (1A): 459-464.



12. Charvalos E, Tsatsakis A, Tzatzarakis M, Dolapsakis G, Stiakakis I. New nystatin polymeric complexes and their in vitro antifungal evaluation in a model study with Fusarium oxysporum. MYCOPATHOLOGIA 2002, 153 (1): 15-19.

11. Tsakiris IN, Toutoudaki M, Nikitovic DP, Danis TG, Stratis I, Tsatsakis AM. Field study for degradation of methyl parathion in apples cultivated with integrated crop management system. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 2002, 69 (6): 771-778.

10. Shtilman MI, Tsatsakis AM, Alegakis AK, Shashkova I, Rizos A, Krambovitis E. Structure vs release-rate relationships in polymeric esters of plant growth regulators. JOURNAL OF MATERIALS SCIENCE 2002, 37 (21): 4677-4682.

9. Alifragis J, Rizos AK, Tsatsakis AM, Tzatzarakis M, Shtilman M. New polymeric systems with controlled release action: a light scattering investigation. JOURNAL OF NON-CRYSTALLINE SOLIDS 2002, 307: 882-886.

8. Baritaki S, Krambovitis E, Alifragis J, Rizos A, Tsatsakis AM. Immunoreactivity and light scattering studies of polyvinyl pyrrolidone polymeric derivatives. JOURNAL OF NON-CRYSTALLINE SOLIDS 2002, 307: 898-904.

7. Tzanakakis GN, Krambovitis E, Tsatsakis AM, Yezeridis P. The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. INTERNATIONAL JOURNAL OF GASTROINTESTINAL CANCER 2002, 32 (1): 23-30.

6. Tsatsakis AM, Tsakiris IN, Maxaira K, Christakis M, Tzanakaki D, Niklis N. Assessment of safe harvesting after methyl parathion application in peaches. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 2002, 68 (6): 824-830.

5. Hatzidakis GI, Tsatsakis AM, Krambovitis EK, Spyros A, Eremin S. Use of L-lysine fluorescence derivatives as tracers to enhance the performance of polarization fluoroimmunoassays. A study using two herbicides as model antigens. ANALYTICAL CHEMISTRY 2002, 74 (11): 2513-2521.

4. Covaci A, Tutudaki M, Tsatsakis AM, Schepens P. Hair analysis: another approach for the assessment of human exposure to selected persistent organochlorine pollutants. CHEMOSPHERE 2002, 46 (3): 413-418.

3.Baritaki S, Tzanakakis GN, Alifragis J, Krambovitis E, Tsatsakis AM, Rizos A. Light scattering and in vitro biocompatibility studies of poly (vinyl pyrrolidone) derivatives with amino-acid-dependant groups. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 2002, 63 (6): 830-837.

2. Tsatsakis AM, Bertsias GK, Liakou V, Mammas I, Stiakakis I, Tzanakakis GN. Severe fenthion intoxications due to ingestion and inhalation with survival outcome. HUMAN & EXPERIMENTAL TOXICOLOGY 2002, 21 (1): 49-54.

1. Mitropoulou TN, Tzanakakis GN, Nikitovic D, Tsatsakis AM, Karamanos N. In vitro effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by estrogen receptor-positive and -negative human breast cancer epithelial cells. ANTICANCER RESEARCH 2002, 22 (5): 2841-2846.



12. Charvalos E, Tzatzarakis M, Tsatsakis A, Petrikos G. Controlled release of water-soluble polymeric complexes of sorbic acid with antifungal activities. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2001, 57 (5-6): 770-775.

11. Psaroudakis K, Tzatzarakis MN, Tsatsakis AM, Michalodimitrakis M. The application of histochemical methods to the age evaluation of skin wounds - Experimental study in rabbits. AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY 2001, 22 (4): 341-345.

10. Torchilin VP, Levchenko TS, Whiteman KR, Yaroslavov AA, Tsatsakis AM, Rizos Ak, Michailova EV, Shtilman MI. Amphiphilic poly-N-vinylpyrrolidones: synthesis, properties and liposome surface modification. BIOMATERIALS 2001, 22 (22): 3035-3044.

9. Papanikolaou N, Paspatis G, Dermitzakis A, Tzirzakakis E, Charalambous E, Tsatsakis AM. Neutropenia induced by paraquat poisoning. HUMAN & EXPERIMENTAL TOXICOLOGY 2001, 20 (11): 597-599.

8. Dolapsakis G, Vlachonikolis IG, Varveris C, Tsatsakis AM. Mammographic findings and occupational exposure to pesticides currently in use on Crete. EUROPEAN JOURNAL OF CANCER 2001, 37 (12): 1531-1536.

7. Mieczkowski T, Tsatsakis AM, Kruger M, Psillakis T. The concentration of three anti-seizure medications in hair: the effects of hair color, controlling for dose and age. BMC CLINICAL PHARMACOLOGY 2001, 1(1):2. Epub 2001 Apr 30.

6. Tzatzarakis MN, Tsatsakis AM, Charvalos E, Vakalounakis D. Comparison of in vitro activities of amphotericin, clotrimazole, econazole, miconazole, and nystatin against Fusarium oxysporum. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2001, 36 (3): 331-340.

5. Tsatsakis AM, Bertsias GK, Mammas IN, Stiakakis I, Georgopoulos DB. Acute fatal poisoning by methomyl caused by inhalation and transdermal absorption. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 2001, 66 (4): 415-420.

4. Pataki M, Anatoliotakis N, Tzanakis N, Assithianakis P, Tsatsakis AM, Bouros D. Availability of antidotes in hospital pharmacies in Greece. VETERINARY AND HUMAN TOXICOLOGY 2001, 43 (2): 103-105.

3. Tsatsakis AM, Tzatzarakis MN, Psaroulis D, Levkidis C, Michalodimitrakis M. Evaluation of the addiction history of a dead woman after exhumation and sectional hair testing. AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY 2001, 22 (1): 73-77.

2. Michalodimitrakis EN, Tsiftsis DDA, Tsatsakis AM, Stiakakis I. Sudden cardiac death and right ventricular dysplasia. AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY 2001, 22 (1): 19-22.

1. M Tutudaki, AM Tsatsakis, A Covaci, P Schepens. Hair analysis: an alternative method of assessing exposure to organochlorine pollutants.   



14. Tzatzarakis MN, Tsatsakis AM, Lotter MM, Shtilman MI, Vakalounakis DJ. Effect of novel water-soluble polymeric forms of sorbic acid against Fusarium oxysporum f. sp radicis-cucumerinum. FOOD ADDITIVES AND CONTAMINANTS 2000, 17 (12): 965-971.

13. Ramoutsaki IA, Haniotakis S, Tsatsakis AM. The snake as the symbol of medicine, toxicology and toxinology. VETERINARY AND HUMAN TOXICOLOGY 2000, 42 (5): 306-308.

12. Tsatsakis AM, Psillakis T, Paritsis N. Phenytoin concentration in head hair sections: A method to evaluate the history of drug use. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 2000, 20 (5): 560-573.

11. N Mulvahill, PE Vardos, GE Kochiadakis, NE Igoumenidis, AM Tsatsakis. Amiodarone as a first choice drug. Current Controlled Trials in Cardiovascular Medicine 2, 72002-1545   

10. Alegakis AK, Tzatzarakis MN, Tsatsakis AM, Vlachonikolis IG, Liakou V. In vitro study of oxytetracycline adsorption on activated charcoal. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2000, 35 (5): 559-569.

9. Ramoutsaki IA, Ramoutsakis YA, Haniotakis S, Tsatsakis AM. Remedies used in Hellenic history. VETERINARY AND HUMAN TOXICOLOGY 2000, 42 (4): 238-241.

8. Tzatzarakis M, Tsatsakis AM, Liakou A, Vakalounakis DJ. Effect of common food preservatives on mycelial growth and spore germination of Fusarium oxysporum. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES    2000, 35 (4): 527-537.

7. Vardas PE, Kochiadakis GE, Igoumenidis NE, Tsatsakis AM, Simantirakis EN, Chlouverakis GI. Amiodarone as a first-choice drug for restoring sinus rhythm in patients with atrial fibrillation - A randomized, controlled study. CHEST 2000, 117 (6): 1538-1545.

6. AM Tsatsakis, M Tutudaki, I Stiakakis, M Dimopoulou, M Tzatzarakis. Characterisation of cannabis plants phenotypes from illegal cultivations in Crete.
Bollettino chimico farmaceutico 139 (3), 140   

5. Ramoutsaki IA, Ramoutsakis YA, Tsikritzis MD, Tsatsakis AM. The roots of toxicology: An etymology approach. VETERINARY AND HUMAN TOXICOLOGY 2000, 42 (2): 111-111

4. Rizos AK, Doetschman DC, Dwyer DW, Tsatsakis AM, Shtilman MI. Study of dichlophenac polymeric derivative with 12-DOXYL spin probe. POLYMER 2000, 41 (3): 1131-1138.

3. AM Tsatsakis, M Tzatzarakis. Lectures presented at the 4th Congress of Toxicology in Developing Countries (4th CTOX-DC), Antalya, Turkey, 6-10 November 1999-Sectional hair testing. Judicial and clinical applications
Pure and Applied Chemistry 72 (6), 1057-1066   

2. A Covaci, M Tutudaki, AM Tsatsakis, P Schepens. Hair analysis: another approach for the assessment of human exposure to persistent organochlorine pollutants.  

1. Tsatsakis AM, Tzatzarakis M. Sectional hair testing. Judicial and clinical applications. PURE AND APPLIED CHEMISTRY    2000, 72 (6): 1057-1066.



12. Kokori H, Giannakopoulou CH, Hatzidaki E, Athanaselis S, Tsatsakis AM, Sbyrakis S. An unusual case of lead poisoning in an infant: Nursing-associated plumbism. JOURNAL OF LABORATORY AND CLINICAL MEDICINE 1999, 134 (5): 522-525.

11. Alegakis AK, Tsatsakis AM, Shtilman MI, Lysovenko PL, Vlachonikolis IG. Deactivation of mycotoxins. I. An in vitro study of zearalenone adsorption on new polymeric adsorbents. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 1999, 34 (4): 633-644.

10. Michalodimitrakis M, Christodoulou P, Tsatsakis AM, Askoxilakis I, Stiakakis I, Mouzas A. Death related to midazolam overdose during endoscopic retrograde cholangiopancreatography. AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY  1999, 20 (1): 93-97.

9. MI Shtilman, II Tverdokhlebova, MY Yarmysh, EV Mikhailova, AM Tsatsakis. Amphiphilic derivatives of poly (N-vinylpyrrolidone).
Polymer science. Series B 41 (5-6), 141-144   

8. EN Michalodimitrakis, JDK Zervos, DDA Tsiftsis, A Patsalis, AM Tsatsakis. Scrotal injury from motorcycle accidents.
Journal of Forensic Medicine & Toxicology 16 (1), 1-3   

7. MI Shtilman, M Tzatzarakis, MM Lotter, AM Tsatsakis. Polymeric fungicides: A review.
Polymer science. Series B 41 (7-8), 243-254    

6. MI Shtil'man, II Tverdokhlebova, MY Yarmysh, EV Mikhailova, AM Tsatsakis. Series B-Amphiphilic Derivatives of Poly (N-vinylpyrrolidone).
Vysokomolekuliarnye Soedineniia 41 (5), 906-909   

5. MI Shtil'man, SN Zhavoronkov, M YARMYSH, PS Voskanyan, AM Tsatsakis. Cross-linked Polyvinyl Alcohol Cryogels.
Russian journal of applied chemistry 72 (6), 1051-1054   

4. MI Shtil'man, AM Tzatzarakis, MM Lotter, AM Tsatsakis. Review-Polymeric Fungicides: A Review.
Vysokomolekuliarnye Soedineniia 41 (8), 1363   

3. Relakis K, Sifakis S, Froudarakis G, Papadopoulou E, Michalodimitrakis EN, Koumantakis E, Tsatsakis A. Disposition of pesticides and toxicants in the human reproductive system in cases of acute poisoning. CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY 1999;26(3-4):207-10.

2. AK Rizos, AM Tsatsakis, MI Shtilman, DC Doetschman. Dynamics of self-release polymeric derivatives.

1. Psillakis T, Tsatsakis AM, Christodoulou F, Michalodimitrakis M, Paritsis N, Helidonis E. Carbamazepine levels in head hair of patients under long-term treatment: A method to evaluate the history of drug use. JOURNAL OF CLINICAL PHARMACOLOGY 1999, 39 (1): 55-67.



12.  Rizos AK, Tsatsakis AM, Shtilman MI, Brown W. Dynamic light-scattering study of 3-indolbutyric acid polymeric derivative. POLYMER 1998, 39 (8-9): 1753-1756.

11. AM Tsatsakis, T Psillakis, A Stefis, P Assithianakis, IG Vlahonikolis. Determination of phenytoin in sections of head hair: a preliminary study to evaluate the history of drug use.
Bollettino chimico farmaceutico 137, 459-466   

10. Tsatsakis AM, Manousakis A, Anastasaki M, Tzatzarakis M, Katsanoulas K, Delaki C, Agouridakis P. Clinical and toxicological data in fenthion and omethoate acute poisoning. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 1998, 33 (6): 657-670.

9. AM Tsatsakis. Judicial applications of hair testing for addicts in Crete: sectional hair analysis of heavy heroin abusers. Journal of Clinical Forensic Medicine 5 (3), 109-113   

8. Rizos AK, Tsatsakis AM, Shtilman MI, Brown W. Dynamic light scattering study of 1-naphthylacetic acid polymeric derivative, a novel plant hormone. POLYMER 1998, 39 (20): 4729-4734.

7. Rizos AK, Tsatsakis AM, Shtilman MI, Brown W. Light scattering investigation of self-release polymeric derivatives. JOURNAL OF NON-CRYSTALLINE SOLIDS 1998, 235: 652-657.

6. Christakis-Hampsas M, Tutudakis M, Tsatsakis AM, Assithianakis P, Alegakis A, Katonis PG, Michalodimitrakis ENl. Acute poisonings and sudden deaths in Crete: A five-year review (1991-1996). VETERINARY AND HUMAN TOXICOLOGY 1998, 40 (4): 228-230.

5. Tsatsakis AM, Tutudaki MI, Tzatzarakis MN, Psaroudakis K, Dolapsakis GP, Michalodimitrakis MN. Pesticide deposition in hair: Preliminary results of a model study of methomyl incorporation into rabbit hair. VETERINARY AND HUMAN TOXICOLOGY 1998, 40 (4): 200-203.

4. Kochiadakis GE, Igoumenidis NE, Solomou MC, Parthenakis FI, Christakis-Hampsas MG, Chlouverakis GI, Tsatsakis AM, Vardas PE. Conversion of atrial fibrillation to sinus rhythm using acute intravenous procainamide infusion. CARDIOVASCULAR DRUGS AND THERAPY 1998, 12 (1): 75-81.

3. MI Shtilman, AM Tsatsakis, JC Vlahos, M Dragassaki, IM Shashkova, MM Lotter. Bioactivity of the Polyvinyl Esters of 2, 4-Dichlorophenoxyacetic Acid.
Russian journal of plant physiology 45 (1), 92-95   

2. Michalodimitrakis M, Tsatsakis A. Massive pulmonary embolism by liver tissue. MEDICINE SCIENCE AND THE LAW 1998, 38 (1): 85-87.

1. Tsatsakis AM. More fatal methomyl poisonings in Crete. SCIENCE & JUSTICE 1998, 38 (4): 282-283.   



13. M Michalodimitrakis, A Tsatsakis. The changing status of forensic medicine in Greece. Journal of Clinical Forensic Medicine 4 (4), 159-162

12. AM Tsatsakis, G Dolapsakis, G Troulakis, P Christodoulou, K Relakis. Fatal and non-fatal outcome by accidental intoxication with paint thinner. Journal of Clinical Forensic Medicine 4 (3), 133-137.

11. Tsatsakis AM, Alegakis TK, Chalkiadakis GE, Askoxilakis I, Vlachonikolis I. Comparative pharmacokinetics of ceftriaxone after periincisional and intravenous administration in patients undergoing abdominal surgery. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 1997, 5 (5): 243-251.

10. Michalodimitrakis EN, Tsatsakis AM. Vehicular accidents and cardiac concussion - A traumatic connection. THE AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY : OFFICIAL PUBLICATION OF THE NATIONAL ASSOCIATION OF MEDICAL EXAMINERS 1997,  18 (3): 282-284.

9. Tsatsakis AM, Michalodimitrakis MN, Patsalis AN. MDEA related death in Crete: A case report and literature review. VETERINARY AND HUMAN TOXICOLOGY  1997, 39 (4): 241-244.

8. Tsatsakis AM, Psillakis TK, Tzatzarakis M, Kourtopoulos H, Paritsis N. Carbamazepine levels in the hair of patients under long-term treatment: A preliminary study CLINICA CHIMICA ACTA 1997, 263 (2): 187-195.

7. MN Michalodimitrakis, R La Grange, AM Tsatsakis. Suicide by alcohol overdose. Journal of Clinical Forensic Medicine 4 (2), 91-94.

6. Troulakis G, Tsatsakis AM, Tzatzarakis M, Astrakianakis A, Dolapsakis G, Kostas R. Acute intoxication and recovery following massive turpentine ingestion: Clinical and toxicological data. VETERINARY AND HUMAN TOXICOLOGY 1997, 39 (3): 155-157.

5. Michalodimitrakis MN, Tsatsakis AM, Christakis Hampsas MG, Trikilis N, Christodoulou P. Death following intentional methyl bromide poisoning: Toxicological data and literature review. VETERINARY AND HUMAN TOXICOLOGY 1997, 39 (1): 30-34.

Proceedings of the Controlled Release Society   

Chimika Chronika-New Series 26 (2), 197-197   

2. Kumantakis E, Makrigiannakis A, Matalliotakis I, Neonaki M, Tsatsakis A. Penetration of pesticides in the human reproductive system. Presentation of case reports. CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY 1997;24(2):86-87.

1. MI Shtilman, AM Tsatsakis, JC Vlahos, AA Khachanyan, M Dragassaki, PS. Hydrolysis and biological activity in a series of water-soluble polymeric esters of aryl-containing carboxylic acids
Polymer science. Series A, Chemistry, physics 39 (11), 1173-1177.



10. Tsatsakis AM, Aguridakis P, Michalodimitrakis MN, Tsakalov AK, Alegakis AK, Koumantakis E, Troulakis G. Experiences with acute organophosphate poisonings in Crete. VETERINARY AND HUMAN TOXICOLOGY 1996, 38 (2): 101-107.   

9. Tsatsakis AM, Perakis K, Koumantakis E. Experience with acute paraquat poisoning in Crete. VETERINARY AND HUMAN TOXICOLOGY 1996, 38 (2): 113-117.   

8. IE Vlachakis, AK Alegakis, GI Vardalachakis, GI Andreadakis, AM Tsatsakis. Essai d'amelioration de la grosseur des baies des raisins apyrenes, par une formulation polymerique a action progressive, utilisant la BAP comme molecule active.
Progres Agricole et Viticole 113   

7. IE Vlachakis, AK Alegakis, GI Vardalachakis, GI Andreadakis, AM Tsatsakis. Improvement assay of the berry size of seedless grapes by a polymeric formulation with progressive action using BAP as active molecule.
Progres Agricole et Viticole 113.

6. MI Shtilman, M Tzatzarakis, JC Vlahos, IM Shashkova, M Dragassaki, AM Tsatsakis. PHYTOACTIVE POLYMERS: HYDROLYSIS AND BIOACTIVITY
Proceedings of the Controlled Release Society.

5. A Psillakis, I Daskalakis, G Kliafas, N Aivalis, S Petrutsu, S Zervu, AM Tsatsakis. Determination of phenytoin in human head hair.
Chimika Chronika-New Series 25 (3), 120-120.

4. AM Tsatsakis, MI Shtil'man, F Alegakis, MY Yarmysh, TS Golubeva. Stability of the Polymeric Salts of Biologically Active Amines.
Vysokomolekuliarnye Soedineniia 38 (8), 1431-1434.

3. MI Shtilman, AM Tsatsakis, AA Khachanyan, PS Voskanyan, M Selala, IM Shashkova. Hydrolysis of polyvinyl esters of biologically active carboxylic acids.
Polymer science. Series B 38 (5-6), 268-271.

2. Tsatsakis AM, Tsakalof AK, Michalodimitrakis EN. The analysis of methomyl, a carbamate pesticide, in post-mortem samples. SCIENCE AND JUSTICE - JOURNAL OF THE FORENSIC SCIENCE SOCIETY 1996, 36 (1): 41-45.

1. Tsatsakis AM, Tsakalof AK, Siatitsas Y, Michalodimitrakis EN. Acute poisoning with carbamate pesticides: The Cretan experience. SCIENCE AND JUSTICE - JOURNAL OF THE FORENSIC SCIENCE SOCIETY 1996, 36 (1): 35-39.



6. Bouros D, Agouridakis P, Tsatsakis AM, Askitopoulou E, Siafakas NM. Orthodeoxia and platypnoea after acute organophosphorus poisoning reversed by cpap - a newly described cause and review of the literature. RESPIRATORY MEDICINE 1995, 89 (9): 625-628.

5. Chalkiadakis GE, Gonnianakis C, Tsatsakis AM, Tsakalof A, Michalodimitrakis M. Preincisional single-dose ceftriaxone for the prophylaxis of surgical-wound infection. AMERICAN JOURNAL OF SURGERY 1995, 170 (4): 353-355.

4. Tsatsakis AM, Paritsis KN, Shtilman MI. 1-naphthylacetic acid slow-release polymeric formulations - auxin type effect in tobacco leaf segments is affected by structure and hydrolysis. PLANT GROWTH REGULATION 1995, 17 (2): 167-175.

3. JC Vlahos, M Dragassaki, A Vasilaki, I Assargiotaki, AM Tsatsakis. The Effect of Slow-release Polymeric Derivatives of Auxins (NAA and 2, 4-D) on Regeneration of Achimenes in Vitro.
HortScience 30 (4), 802-802   

2. M Selala, AM Tsatsakis, A Alegakis, A Musuku, M Lotter, F Manirakiza, P Sche. Slow release froms of sec-butylamine: hydrolysis and application in the control of pathogenic fungi.

1. MI Shtil'man, MB Sarkisyan, AM Tsatsakis, IM Shashkova, E Mikhalodimitrakis. Water-Soluble Polymeric Esters of Carboxyl-Containing Plant Growth Regulators.
Polymer Science-Series A 37 (1), 22-27.



5. AM Tsatsakis, EI Vlachakis, IM Shtilman, MI Shashkova, SRIN Allakhverdiev. Water soluble polymeric systems of phytohormones with slow release: synthesis and application.
EP Patent 0,609,638

4. Musuku A, Selala MI, Debruyne T, Claeys M, Schepens PJC, Tsatsakis A, Shtilman MI. Isolation and structure determination of a new roquefortine-related mycotoxin from penicillium-verrucosum var cyclopium isolated from cassava. JOURNAL OF NATURAL PRODUCTS 1994, 57 (7): 983-987.

3. AM Tsatsakis, MI Shtilman, MY Jarmish, P Schepens. Bandages with immobilised indomethacin: preparation, toxicology, application.

2. AM Tsatsakis, MI Shtilman, AL Chimishkyan, P Schepens. Polymeric derivatives of biologically active carbamates.

1. Tsatsakis AM, Shtilman MI. Polymeric derivatives of plant growth-regulators - synthesis and properties. PLANT GROWTH REGULATION 1994, 14 (1): 69-77.



2. Kornakov MY, Tsatsakis AM, Davidovich YA, Shtilman MI. Synthesis of 1-aminocyclopropane-1-carboxylic acid functional-derivatives. MENDELEEV COMMUNICATION 1993, (5): 214-215.

1. Kalinin AV, Shapiro EA, Tomilov YV, Ugrak B, Tsatsakis AM, Nefedov O. Selective noncatalytic cyclopropanation of methyl (e)-pent-3-en-1-yn-3-ylcarboxylates with diazomethane. MENDELEEV COMMUNICATION 1993, (5): 190-191.



2. MI SHTIL'MAN, M YA, MY KORNAKOV, AM TSATSAKIS, NV KURUSHINA, TP ZALUKAEVA. Polymeric derivatives of 1-aminocyclopropane-1-carboxylic acid.
Polymer science 34 (10), 827-830

1. MI Shtil’man, MY Kornakov, AM Tsatsakis, NV Kurushina, TP Zalukaeva. POLYMER DERIVATIVES OF 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID.
Высокомолекулярные соединения 34 (10), 17-22



7. Tsatsakis AM, Dais P. H-1-nmr structural-analysis of a series of naphthalene-hydroxymethyl-carboxylic and naphthalene-mercaptomethyl-carboxylic acids and derivatives. MAGNETIC RESONANCE IN CHEMISTRY 1990, 28 (4): 375-377.

6. M Michalakis, G Heretis, E Chrysos, AM Tsatsakis. Pesticides Exposure and Risk of Hypospadias.

5. A Kuskov, M Shtilman, A Villemson, N Larionova, AM Tsatsakis. Amphiphilic poly-N-vinylpyrrolidone nano-carriers for protein encapsulation.

4. Alexandr A Artyukhov, Vasiliy S Kozlov, Mikhail V Khazanchuk, Ilya A Fadushin, Aristidis M Tsatsakis, Mikhail I Shtilman. Due to the porous structure features gels are stable in the solutions with different ionic force. Microscopic study of gels shows that they contain transparent pores with the size of tens and hundreds of microns according to synthesis conditions. Studying of synthesized polymer systems in water saturated condition by structure-dynamic method shows that with the application of load we can observe two deformation areas, first for extrusion from macropores and second for deformation of cross-linked areas. Using this data the distances between polymer phase lacing knots were calculated. Their values lay between 20000-60000 D. Presence of highly reactive epoxy groups in polymers enables the immobilization of different proteins in mild conditions without extra activation of the carrier. Studying of the immobilization conditions influence on the amount of immobilized albumin allows discovering of optimal process parameters and shows that amount of immobilized protein reaches 150 mg/g of the carrier.

3. Olga V Suprun, Mikhail M Lotter, Mikhail I Shtilman, Aristidis M Tsatsakis. As it was shown, polymeric complexes of SA possess higher level of activity than low-molecular acid. At the same time level of activity increased with the decreasing of polymeric carrier molecular weight. Polymeric esters of SA, prepared by interaction of acid and water-soluble polymeric epoxy-containing carriers with different molecular weight show lower fungicidal activity than polymeric complexes of acid. Lower activity of systems in which acid was bind by covalent (ester) bond is based on lower speed of polymers hydrolysis. Speed of hydrolysis of these polymeric ethers was analyzed by HPLC method.

2. MI Shtil'man, Yu V Korshak, PS Voskanyan, E Tzatzarakis, IA Grigoryuk, N Sh Ormotsadze, AM Tsatsakis, GG Allan. FITOAKTIVNYE POLIMERY.

1. MN TZATZARAKIS, AM TSATSAKIS. Organochlorine and Organophosphate Pes-ticides Monitoring in Non Conventional Biological Samples. Medical Management of Chemical and Biological Casualties, 221



8.Stiakakis I., Belivanis S.D., Tzatzarakis M.N., Fragoulis M., Tsatsakis A.M. Disputed case of homicide by smothering due to severe amitriptyline intoxication of the victim. JOURNAL OF FORENSIC AND LEGAL MEDICINE 2009, 16 (5), 280-283

7. Sifakis S, Angelakis E, Makrigiannakis A, Orfanoudaki I, Christakis-Hampsas M, Katonis P, Tsatsakis A, Koumantakis E. Chemoprophylactic and bactericidal efficacy of 80 mg gentamicin in a single and once-daily dosing. ARCHIVES OF GYNECOLOGY AND OBSTETRICS 2005, 272(3):201-206. Epub 2004 Dec 17.

6. Tsatsakis AM, Psillakis T, Stefis A, Assithianakis P, Vlahonikolis IG, Michalodimitrakis MN, Helidonis E. Determination of phenytoin in sections of head hair: a preliminary study to evaluate the history of drug use. BOLLETTINO CHIMICO FARMACEUTICO 1998, 137(11):459-466.

5. Tsatsakis AM. Judicial applications of hair testing for addicts in Crete: Sectional hair analysis of heavy heroin abusers. JOURNAL OF CLINICAL FORENSIC MEDICINE. 1998, VOL 5(3), 109-113.

4. Tsatsakis AM, Tutudaki M, Stiakakis I, Dimopoulou M, Tzatzarakis M, Michalodimitrakis M. Characterisation of cannabis plants phenotypes from illegal cultivations in Crete. BOLLETTINO CHIMICO FARMACEUTICO 2000, 139(3):140-145.

3. Michalodimitrakis M. Tsatsakis A. The changing status of forensic medicine in Greece. JOURNAL OF CLINICAL FORENSIC MEDICINE 1997, 4(4): 159-162.

2. Michalodimitrakis MN. La Grange R. Tsatsakis AM. Suicide by alcohol overdose. JOURNAL OF CLINICAL FORENSIC MEDICINE 1997, 4(2): 91-94.

1. Tsatsakis AM. Dolapsakis G. Troulakis G. Christodoulou P. Relakis K. Trikilis N. Michalodimitrakis M. Fatal and non-fatal outcome by accidental intoxication with paint thinner. JOURNAL OF CLINICAL FORENSIC MEDICINE 1997, 4(3):133-137.



21.Tashmukhamedov, R.I., Shtil'man, M.I., Khvostova, V.Yu., Klyagina, M.V., Tsatsakis, A.M., Shashkova, I.M. Poly(N-vinylpyrrolidone) with amino acid side groups. POLYMER SCIENCE SERIES B 2005, 47 (5-6), 167-169

20. Kuskov A.N., Shtil'man M.I., Tsatsakis A.M., Torchilin V.P., Yamskov I.A Synthesis of amphiphilic N-vinylpyrrolidone and acrylamide polymers of various structures. RUSSIAN JOURNAL OF APPLIED CHEMISTRY, 2005,78 (5), pp. 806-810

19. Shtilman MI, Tzatzarakis M, Lotter MM, Tsatsakis AM. Polymeric fungicides: A review. VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A & SERIYA 1999, B 41 (8): 1363-1376.

18. Shtilman MI, Tverdokhlebova II, Yarmysh MY, Mikhailova EV, Tsatsakis AM, Tocchilin VP, Rizos AK. Amphiphilic derivatives of poly(N-vinylpyrrolidone). VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A & SERIYA 1999, B 41 (5): 906-909.

17. Shtilman MI, Zhavoronkov SN, Yarmysh MY, Tsatsakis AM. Cross-linked polyvinyl alcohol cryogels. RUSSIAN JOURNAL OF APPLIED CHEMISTRY 1999, 72 (6): 1051-1054.

16. Shtilman MI, Tsatsakis AM, Vlahos JC, Dragassaki M, Shashkova IM, Lotter MM. Bioactivity of the polyvinyl esters of 2,4-dichlorophenoxyacetic acid. RUSSIAN JOURNAL OF PLANT PHYSIOLOGY 1998, 45 (1): 92-95.

15. Shtilman MI, Tsatsakis AM, Vlahos JC, Khachanyan AA, Dragasaki M, Voskanyan PS, Shashkova IM. Hydrolysis and biological activity in a series of water-soluble polymeric esters of aryl-containing carboxylic acids. VYSOKOMOLEKULARNYE SOEDINENIYA. SER.A SER.B SER.C - KRATKIE SOOBSHCHENIYA 39 (11): 1761-1766 NOV 1997 (IF1999: 0.627).

14. Shtilman MI, Tsatsakis AM, Khachanyan AA, Voskanyan PS, Selala M, Shashkova IM. Hydrolysis of polyvinyl esters of biologically active carboxylic acids. VYSOKOMOLEKULARNYE SOEDINENIYA. SER.A SER.B SER.C - KRATKIE SOOBSHCHENIYA 1996, 38 (6): 1076-1079.

13. Tsatsakis AM, Shtilman MI, Alegakis F, Yarmysh MY, Golubera TS. Stability of the polymeric salts of biologically active amines. VYSOKOMOLEKULARNYE SOEDINENIYA. SER.A SER.B SER.C - KRATKIE SOOBSHCHENIYA 1996, 38 (8): 1431-1434.

12. Shtilman MI, Sarkisyan MB, Tsatsakis AM, Shashkova IM, Mikhalodimitrakis E, Dais F. Water-soluble polymeric esters of carboxyl-containing plant-growth regulators. VYSOKOMOLEKULARNYE SOEDINENIYA. SER.A SER.B SER.C - KRATKIE SOOBSHCHENIYA 1995, 37 (1): 29-34.

11. Shtilman MI, Tsatsakis AM, Yarmysh MY. Polymer esters of indomethacin. IZV VUZ KHIM KH TEKH 1995, 38 (1-2): 107-114.

10. Shtilman MI, Kosharnaya OP, Schepens P Tsatsakis AM. Copolymers of n-vinylpyrrolidone and 2-methylene-1,4,6-trioxaspiro-[5,5]-nonane. IZV VUZ KHIM KH TEKH 37 (10-12): 108-113 1994.

9. Kornakov MY, Tsatsakis AM, Davidovich YA. Synthesis of 1-aminocyclopropane-1-carboxylic acid and several of its derivatives. IZV VUZ KHIM KH TEKH 1993, 36 (1): 13-20.

8. Tsatsakis AM, Shtilman MI, Sarkisyan MB. Kinetics of the interaction of potassium-salts of a phytoactive carboxylic-acid series with ethylene chlorohydrine. IZV VUZ KHIM KH TEKH 1993, 36 (1): 42-45.

7. Shtilman MI, Kornakov MY, Tsatsakis AM, Kuruskina NV, Zalukaeva TP. Polymer derivatives of 1-aminocyclopropane-1-carboxylic acid. VYSOKOMOLEKULARNYE SOEDINENIYA. SER.A SER.B SER.C - KRATKIE SOOBSHCHENIYA 34 (10): 17-22 Oct 1992 (IF1993: 0.627).

6. Tsatsakis AM, Shashkova IM, Shtilman MI. Hydrolysis of polymer esters of 1-naphthylacetic acid. VYSOKOMOLEKULARNYE SOEDINENIYA. SER.A SER.B SER.C - KRATKIE SOOBSHCHENIYA 1992, 34 (11): 32-36.

5. Listitsyn VN, Tsatsakis AM, Trushkina TV. 2,6-( carboxymethyloxy), 2,7-(carboxymethyloxy) and 1,5-(carboxymethyloxy), (carboxymethyl-mercapto) naphthalene. ZHURNAL ORGANICHESKOI KHIMII 1987, 23 (9): 1942-1948.

4.Lisitsyn VN, Tsatsakis AM. Certain transformations of 2,6-di (carboxymethylthio)naphthalenes and 2,7-di(carboxymethylthio) naphthalenes. ZHURNAL ORGANICHESKOI KHIMII 1990, 26 (5): 1095-1100.

3.Lisitsyn VN, Tsatsakis AM. Nitration of 2,6-di (carboxymethyl-sulfonyl)naphthalenes and 2,7-di(carboxymethylsulfonyl) naphthalenes. IZV VUZ KHIM KH TEKH 1989, 32 (8): 119-121.

2.Lisitsyn VN, Tsatsakis AM. Nitration of 2,6-(carboxymethyloxy), 2,7-(carboxymethyloxy) and 1,5-(carboxymethyloxy), (carboxymethylmercapto) naphthalenesn. ZHURNAL ORGANICHESKOI KHIMII 1987, 23 (10): 2208-2212.

1.Lisitsyn VN, Kukalenko LS, Tsatsakis AM. Synthesis and some transformations of (2,7-naphthylene and 2,6-naphthylene)bisthioacetic acids. ZHURNAL ORGANICHESKOI KHIMII 1985, 21 (1): 161-164.

Professor Tsatsakis is Director at the Toxicology Science and Research Centre in the Department of Forensic Sciences of the Medical School in the University of Crete and The University Hospital.